【摘要】：目的探討輔助生殖技術(shù)中異位妊娠(EP)的發(fā)生率、影響因素和早期診療、防治的方法。方法回顧性分析體外受精-胚胎移植(IVF-ET)、卵胞漿內(nèi)單精子顯微注射(ICSI)、胚胎植入前遺傳學(xué)診斷(PGD)和凍融胚胎移植(FET)治療后86例EP患者的臨床資料。結(jié)果共有2 903個(gè)周期獲臨床妊娠,86例EP,發(fā)生率2.96%,其中包括宮內(nèi)宮外同時(shí)妊娠4例(4.65%)。患者年齡、不孕年限、體重指數(shù)、是否合并排卵障礙、男方因素不孕、染色體異常、既往分娩史、獲卵數(shù)、移植胚胎數(shù)目、移植管進(jìn)入宮腔深度對(duì)EP的發(fā)生影響不大。輸卵管盆腔病變、子宮內(nèi)膜異位癥及其術(shù)后與EP的發(fā)生有顯著的關(guān)聯(lián)(OR=11.457,P=0.000;OR=3.479,P=0.002)。子宮內(nèi)膜厚度≥7.5 mm時(shí),輸卵管妊娠風(fēng)險(xiǎn)則有所下降(OR=10.463,P=0.002)。結(jié)論輸卵管盆腔病變,子宮內(nèi)膜異位癥及其術(shù)后,移植日子宮內(nèi)膜厚度是EP發(fā)生的重要影響因素。妊娠早期血人絨毛膜促性腺激素(HCG)監(jiān)測(cè)結(jié)合陰道B超檢查是EP主要的早期診斷方法。
[Abstract]:Objective to investigate the incidence, influencing factors, early diagnosis and treatment, prevention and treatment of ectopic pregnancy (EP) in assisted reproductive technology. Methods the clinical data of 86 patients with EP after in vitro fertilization and embryo transfer (IVF-ET), intracytoplasmic sperm microinjection (ICSI), embryo implantation genetics and frozen and thawed embryo transfer (FET) were analyzed retrospectively. Results there were 2 903 cycles of clinical pregnancy, 86 cases of EP, occurred 2.96%, including 4 cases of intrauterine pregnancy (4.65%). Age, length of infertility, body mass index (BMI), male factor infertility, chromosome abnormality, previous delivery history, number of eggs acquired, number of embryos transferred, depth of transfer tube into uterine cavity had little effect on the occurrence of EP. Fallopian tube pelvic lesions, endometriosis and postoperative EP have a significant correlation (OR=11.457,P=0.000;OR=3.479,P=0.002). The risk of tubal pregnancy decreased with endometrial thickness 鈮，

本文編號(hào)：2369627