妊娠期糖尿病診斷與治療研究進(jìn)展
發(fā)布時間:2018-11-26 15:24
【摘要】:GDM是指妊娠期間發(fā)生的不同程度的糖代謝異常,不包括妊娠前即存在的糖尿病或糖尿病前期,是常見的妊娠并發(fā)癥。GDM診斷標(biāo)準(zhǔn)歷經(jīng)變遷,但全球一直缺乏統(tǒng)一的診斷標(biāo)準(zhǔn),直至2008年高血糖與不良妊娠結(jié)局(HAPO)研究公布,國際糖尿病與妊娠研究組(IADPSG)制定了新的GDM診斷標(biāo)準(zhǔn)。該標(biāo)準(zhǔn)逐漸成為全球公認(rèn)的診斷標(biāo)準(zhǔn),我國于2011年采納此標(biāo)準(zhǔn)。人胰島素是GDM治療一線用藥,近些年胰島素類似物,如門冬、地特胰島素已獲批準(zhǔn),口服降糖藥尤其二甲雙胍的安全性、有效性得到越來越多的證實。本文將針對GDM診斷與治療進(jìn)行綜述。
[Abstract]:GDM refers to different degrees of abnormal glucose metabolism occurring during pregnancy, not including diabetes mellitus or pre-diabetes that exists before pregnancy, and is a common complication of pregnancy. The diagnostic criteria of GDM have undergone changes, but the global diagnostic criteria have been lacking of a unified diagnostic standard. Until the 2008 (HAPO) study on hyperglycemia and adverse pregnancy outcomes, the International Diabetes and pregnancy study Group (IADPSG) developed a new diagnostic standard for GDM. This standard has gradually become a globally accepted diagnostic standard, which was adopted in China in 2011. Human insulin is a first-line drug in the treatment of GDM. In recent years, insulin analogues such as Aspergillus and Dietate have been approved. The safety and efficacy of oral hypoglycemic drugs, especially metformin, have been proved more and more. This article reviews the diagnosis and treatment of GDM.
【作者單位】: 北京大學(xué)第一醫(yī)院內(nèi)分泌科;
【分類號】:R714.256
[Abstract]:GDM refers to different degrees of abnormal glucose metabolism occurring during pregnancy, not including diabetes mellitus or pre-diabetes that exists before pregnancy, and is a common complication of pregnancy. The diagnostic criteria of GDM have undergone changes, but the global diagnostic criteria have been lacking of a unified diagnostic standard. Until the 2008 (HAPO) study on hyperglycemia and adverse pregnancy outcomes, the International Diabetes and pregnancy study Group (IADPSG) developed a new diagnostic standard for GDM. This standard has gradually become a globally accepted diagnostic standard, which was adopted in China in 2011. Human insulin is a first-line drug in the treatment of GDM. In recent years, insulin analogues such as Aspergillus and Dietate have been approved. The safety and efficacy of oral hypoglycemic drugs, especially metformin, have been proved more and more. This article reviews the diagnosis and treatment of GDM.
【作者單位】: 北京大學(xué)第一醫(yī)院內(nèi)分泌科;
【分類號】:R714.256
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