【摘要】：正干細(xì)胞因子(SCF)是一種廣泛分布于骨髓、腎、卵巢等器官的多功能細(xì)胞因子,通過與Ⅲ型酪氨酸激酶受體c-kit結(jié)合,激活下游信號傳導(dǎo)途徑,影響細(xì)胞增殖、分化、遷移、凋亡等系列活動[1]。最初因發(fā)現(xiàn)SCF可刺激干細(xì)胞分化成不同譜系的血細(xì)胞而成為重要的造血細(xì)胞調(diào)節(jié)因子[2]。SCF參與卵巢顆粒細(xì)胞、泡膜細(xì)胞、間質(zhì)細(xì)胞、子宮內(nèi)膜上皮細(xì)胞、胚胎滋養(yǎng)細(xì)胞增殖、分化、存活,卵母細(xì)胞
[Abstract]:Positive stem cell factor (SCF) is a multifunctional cytokine widely distributed in bone marrow, kidney, ovary and other organs. It activates downstream signal transduction pathway by binding to type 鈪，

本文編號：2314695