【摘要】：目的探討血栓前狀態(tài)致復(fù)發(fā)性流產(chǎn)的臨床危害和診療方法。方法選擇84例血栓前狀態(tài)致復(fù)發(fā)性流產(chǎn)患者隨機分為兩組,應(yīng)用阿司匹林治療組(對照組)42例,阿司匹林聯(lián)合低分子肝素治療組(觀察組)42例,比較兩組患者治療前、后的流產(chǎn)率、早產(chǎn)率、足月產(chǎn)率的妊娠結(jié)局;對兩組孕婦治療前、后抗凝血酶Ⅲ、D-二聚體、凝血酶時間等指標(biāo)進行檢驗比較以及兩組在出血、血小板減少、瘀斑等不良反應(yīng)的發(fā)生進行比較。結(jié)果兩組流產(chǎn)率、早產(chǎn)率、足月產(chǎn)率的妊娠結(jié)局比較差異有統(tǒng)計學(xué)意義(P0.05);兩組患者治療前、后D-二聚體、抗凝血酶Ⅲ(AT-Ⅲ)、凝血酶時間(TT)等血栓性檢驗指標(biāo)比較差異有統(tǒng)計學(xué)意義(P0.05);兩組患者治療前、后出血、血小板減少、瘀斑等不良反應(yīng)的發(fā)生率比較差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論阿司匹林聯(lián)合低分子肝素治療由血栓前狀態(tài)導(dǎo)致的復(fù)發(fā)性流產(chǎn)有良好的臨床意義。
[Abstract]:Objective to investigate the clinical harm and diagnosis and treatment of recurrent abortion caused by prethrombotic state. Methods Eighty-four patients with recurrent abortion caused by prethrombotic state were randomly divided into two groups: the control group (n = 42) and the control group (n = 42). The pregnancy outcome of abortion rate, preterm delivery rate and term delivery rate after treatment were compared between the two groups of pregnant women before and after treatment of anti-thrombin 鈪，

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