【摘要】：目的探討陜西省漢中地區(qū)婦女人群人乳頭瘤病毒(human papillomavirus,HPV)亞型分布特征。方法采用聚合酶鏈反應(yīng)(polymerase chain reaction,PCR)反向點雜交法對HPV感染進(jìn)行分型檢測。結(jié)果漢中地區(qū)婦女人群HPV感染率為29.86%,高危、低危、高低危感染率分別為26.79%、1.57%和1.49%。高危單一和多重感染分別占總?cè)巳旱?1.08%和5.71%。在≤20歲和60歲年齡組均有較高感染率,在21歲各組中隨年齡增長感染率逐步升高。高危型感染率在51~歲年齡組為最高�？傮w和單一常見亞型為16、58、52、53、33、39型,分別占總體感染73.25%和79.71%,16亞型分別占27.11%和34.41%;多重常見亞型為16、52、58、53、39和33型,占多重感染的64.75%,16亞型占17.51%。單一占總感染的75.66%,高危單一占70.59%;多重占總感染的24.34%,高危多重占24.13%。在多重感染中以二重高危感染最為多見,占多重感染的72.50%。結(jié)論漢中地區(qū)婦女人群HPV感染率較高,其常見高危亞型為16,58,52,53,33,39型,低危型為6和43型。不同年齡段的亞型分布各有不同。HPV總體感染、高危、低危和高低危混合感染率在不同年齡段均有差異。
[Abstract]:Objective to investigate the distribution of human papillomavirus (human papillomavirus,HPV) subtypes in women in Hanzhong area of Shaanxi Province. Methods polymerase chain reaction (polymerase chain reaction,PCR) reverse dot hybridization was used to detect HPV infection. Results the infection rate of HPV in women in Hanzhong area was 29.860.The infection rate of high and low risk was 26.79% and 1.49%, respectively. High risk single infection and multiple infection accounted for 21.08% and 5.71% of the total population, respectively. The infection rate was higher in the age group of 鈮，

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