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胚胎晚期暴露脂多糖對(duì)中年CD-1小鼠背側(cè)海馬SUMO-3含量的影響

發(fā)布時(shí)間:2018-09-10 10:39
【摘要】:為探討胚胎晚期暴露細(xì)菌脂多糖(LPS)的中年CD-1小鼠背側(cè)海馬的類泛素化蛋白(SUMO-3)含量有無(wú)年齡相關(guān)性改變。采用免疫組織化學(xué)技術(shù)檢測(cè)LPS暴露組和對(duì)照組CD-1小鼠背側(cè)海馬DG區(qū)、CA1區(qū)和CA3區(qū)各亞層的SUMO-3表達(dá)。結(jié)果表明,兩組間各區(qū)各亞層的SUMO-3含量無(wú)明顯差異。
[Abstract]:To investigate the age-related changes in the content of ubiquitin (SUMO-3) in the dorsal hippocampus of CD-1 mice exposed to bacterial lipopolysaccharide (LPS) in late embryonic stage. Immunohistochemical technique was used to detect the expression of SUMO-3 in the DG and CA3 sublayers of the dorsal hippocampus of CD-1 mice in LPS exposed group and control group. The results showed that there was no significant difference in SUMO-3 content between the two groups.
【作者單位】: 安徽醫(yī)科大學(xué)第一附屬醫(yī)院重癥醫(yī)學(xué)科;安徽醫(yī)科大學(xué)附屬巢湖醫(yī)院神經(jīng)內(nèi)科和全科醫(yī)學(xué)科;
【基金】:國(guó)家自然科學(xué)基金(81370444) 安徽省高校自然科學(xué)研究項(xiàng)目(KJ2015A126)資助
【分類號(hào)】:R714.2
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本文編號(hào):2234200

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