【摘要】：目的:對復(fù)發(fā)性流產(chǎn)(RSA)綜合保胎治療成功患者進(jìn)行回顧性分析,對母嬰安全性進(jìn)行評估。方法:選擇天津醫(yī)科大學(xué)寶坻臨床學(xué)院(我院)2012年6月—2015年6月,年齡小于35歲,孕早期住院予綜合保胎治療成功的,并且于我院分娩的RSA患者105例作為研究對象(觀察組);選擇同期無自然流產(chǎn)史、未經(jīng)保胎治療于我院分娩的孕婦105例作為對照組。觀察2組產(chǎn)婦妊娠并發(fā)癥、出血、羊水、胎兒、新生兒情況,新生兒隨訪至生后12周。結(jié)果:觀察組妊娠期高血壓、胎膜早破發(fā)生率低于對照組,差異有統(tǒng)計(jì)學(xué)意義(均P0.05)。2組產(chǎn)婦妊娠期糖尿病、前置胎盤、產(chǎn)后出血發(fā)生率差異無統(tǒng)計(jì)學(xué)意義(均P0.05)。排除死胎及畸形引產(chǎn),2組產(chǎn)婦出血量、羊水情況評分比較差異無統(tǒng)計(jì)學(xué)意義(均P0.05)。2組新生兒評分,性別比,早產(chǎn)、巨大兒、新生兒出生缺陷、12周黃疸發(fā)生率差異均無統(tǒng)計(jì)學(xué)意義(均P0.05)。2組產(chǎn)婦足月分娩孕周和孕足月新生兒出生體質(zhì)量比較差異無統(tǒng)計(jì)學(xué)意義(均P0.05)。結(jié)論:RSA綜合保胎治療安全有效,未發(fā)現(xiàn)對母嬰產(chǎn)生不良影響,可以臨床推廣。
[Abstract]:Objective: to evaluate the safety of (RSA) for recurrent abortion. Methods: from June 2012 to June 2015, Baodi Clinical College of Tianjin Medical University, aged less than 35 years, was selected to be hospitalized in early pregnancy and successfully treated with comprehensive fetal preservation. 105 cases of RSA patients in our hospital were chosen as the study object (observation group), and 105 cases of pregnant women who had no history of spontaneous abortion and had not been treated with fetal protection were selected as the control group. Pregnancy complications, hemorrhage, amniotic fluid, fetus and newborn were observed in both groups. The neonates were followed up to 12 weeks after birth. Results: the incidence of hypertension and premature rupture of membranes in the observation group was lower than that in the control group (P0.05). There was no significant difference in the incidence of gestational diabetes mellitus, placenta previa and postpartum hemorrhage in the observation group (P0.05). There was no significant difference in blood loss and amniotic fluid score between the two groups excluding stillbirth and abnormal induced labor (P0.05). There was no significant difference in the incidence of jaundice at the 12th week of neonatal birth defect (P0.05). 2. There was no significant difference in the birth weight of full-term delivery and gestational term newborns in group 2 (P0.05). Conclusion it is safe and effective to treat the fetus with: RSA, no adverse effect on mother and child has been found, and can be popularized in clinic.
【作者單位】： 天津醫(yī)科大學(xué)總醫(yī)院;天津醫(yī)科大學(xué)寶坻臨床學(xué)院;
【分類號】：R714.21

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