【摘要】：目的:探討年輕女性體外受精-胚胎移植(IVF-ET)長(zhǎng)方案周期累積活產(chǎn)率的影響因素。方法:回顧性分析首次接受IVF長(zhǎng)方案助孕治療的1 147例年輕且卵巢儲(chǔ)備功能良好的不孕女性的臨床資料,按完成一次取卵周期是否獲得最終活產(chǎn)胎兒分為活產(chǎn)組與未獲活產(chǎn)組,采用多因素Logistic回歸分析影響累積流產(chǎn)率的相關(guān)因素。結(jié)果:活產(chǎn)組患者的體質(zhì)量指數(shù)(BMI)較未獲活產(chǎn)組顯著降低(P0.05),而獲卵數(shù)、正常受精率及可移植胚胎數(shù)顯著增高(P0.05)。Logistic回歸分析顯示BMI及可移植胚胎數(shù)是年輕且卵巢儲(chǔ)備功能良好的不孕女性首次行IVF長(zhǎng)方案周期獲得累積活產(chǎn)的重要影響因素,BMI24.2 kg/m2及可移植胚胎數(shù)≥5患者的妊娠結(jié)局較佳。結(jié)論:年輕且卵巢儲(chǔ)備功能良好的女性首次IVF長(zhǎng)方案周期中,BMI及可移植胚胎數(shù)與累積活產(chǎn)率顯著相關(guān),較低的BMI及適當(dāng)多的可移植胚胎數(shù)可提高一次取卵周期的累積活產(chǎn)率。
[Abstract]:Aim: to investigate the factors influencing the cumulative long term live births in young women with in vitro fertilization and embryo transfer (IVF-ET). Methods: the clinical data of 1 147 young infertile women with good ovarian reserve function who were first treated with IVF long term regimen were analyzed retrospectively. According to whether the fetuses obtained the final live birth after one cycle of ovulation, they were divided into two groups: live delivery group and non live delivery group. Multivariate Logistic regression analysis was used to analyze the related factors of cumulative abortion rate. Results: the body mass index (BMI) of the patients with live delivery was significantly lower than that of the group without live delivery (P0.05), but the number of eggs obtained was significantly lower than that of the group without live delivery (P0.05). The normal fertilization rate and the number of transferable embryos were significantly increased (P0.05). Logistic regression analysis showed that BMI and the number of transferable embryos were the important factors influencing the cumulative live birth in the first long IVF regimen cycle of young infertile women with good ovarian reserve function. The pregnancy outcome was better in patients with BMI24.2 kg/m2 and number of transferable embryos 鈮，

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