【摘要】：目的:探討臨床藥師在圍產(chǎn)期危重患者藥物治療中的作用。方法:臨床藥師參與4例圍產(chǎn)期危重患者的藥物治療過程,結(jié)合妊娠期及妊娠后特殊的病理生理狀況(如尿素循環(huán)障礙、血脂異常、嚴(yán)重感染和循環(huán)血容量不能快速恢復(fù)等),在權(quán)衡治療矛盾的基礎(chǔ)上,結(jié)合相關(guān)指南和文獻(xiàn)在藥物選擇、用藥時機、用藥療程、聯(lián)合用藥、劑量調(diào)整等方面,針對性地給出選用頭孢呋辛、還原型谷胱甘肽、熊去氧膽酸等藥物,及時停藥或調(diào)整抗菌藥物治療方案等個體化用藥建議,并行實驗室指標(biāo)檢測及不良反應(yīng)監(jiān)測等藥學(xué)監(jiān)護(hù)。結(jié)果:醫(yī)師采納臨床藥師建議,4例患者病情均好轉(zhuǎn)。結(jié)論:臨床藥師在參與圍產(chǎn)期危重患者藥物治療的過程中,應(yīng)選擇安全、有效的治療藥物,并根據(jù)其臨床癥狀及時調(diào)整用藥方案;當(dāng)用藥安全性與藥物有效性矛盾時,應(yīng)充分權(quán)衡利弊,確保孕婦和胎兒的生命安全。
[Abstract]:Objective: to explore the role of clinical pharmacists in the treatment of perinatal critical patients. Methods: clinical pharmacists participated in the treatment of 4 perinatal critical patients, combined with the special pathophysiological conditions during pregnancy and after pregnancy (such as urea circulatory disorder, dyslipidemia). Serious infection and rapid recovery of circulating blood volume, etc.) on the basis of weighing treatment contradictions, combining relevant guidelines and literature on drug selection, timing, course of treatment, combined use of drugs, dose adjustment, etc. Individualized drug suggestions such as cefuroxime, reduced glutathione, ursodeoxycholic acid and so on were given. Results: all the 4 patients were improved according to the advice of the clinical pharmacist. Conclusion: clinical pharmacists should choose safe and effective drugs in the course of taking part in the treatment of perinatal critical patients, and adjust the regimen according to their clinical symptoms. The pros and cons should be fully weighed to ensure the safety of pregnant women and fetuses.
【作者單位】： 上海交通大學(xué)醫(yī)學(xué)院附屬新華醫(yī)院藥學(xué)部;上海交通大學(xué)醫(yī)學(xué)院附屬新華醫(yī)院外科重癥監(jiān)護(hù)病房;
【基金】：新華醫(yī)院院級臨床研究項目(No.15LC11)
【分類號】：R714.7

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 郭艷杰;尚麗新;;妊娠期合理用藥[J];人民軍醫(yī);2016年04期

2 文傳芳;;腺苷蛋氨酸聯(lián)合熊去氧膽酸治療妊娠期膽汁淤積的臨床療效[J];中國醫(yī)藥指南;2015年29期

3 袁琦文;莊圓;陳勇;洪婷;姜芳芳;;產(chǎn)婦圍產(chǎn)期醫(yī)院感染臨床特征與病原菌監(jiān)測分析[J];中華醫(yī)院感染學(xué)雜志;2015年14期

4 孫俊峰;湯親青;張劍林;方茂勇;;高脂血癥性急性胰腺炎的發(fā)病機制及治療的研究進(jìn)展[J];肝膽外科雜志;2014年05期

5 陳泓;張琚芳;朱啟英;;腺苷蛋氨酸聯(lián)合熊去氧膽酸治療妊娠期肝內(nèi)膽汁淤積癥的系統(tǒng)評價[J];中國循證醫(yī)學(xué)雜志;2014年08期

6 王文工;張穩(wěn)健;馬杰;;晚期妊娠婦女纖維蛋白原、D-二聚體及抗凝血酶Ⅲ的檢測及分析[J];臨床輸血與檢驗;2014年02期

7 林e，

本文編號：2163058