【摘要】：目的：通過(guò)新鮮移植周期與冷凍移植周期中非優(yōu)質(zhì)胚胎移植相關(guān)數(shù)據(jù)的分析,探討非優(yōu)質(zhì)胚胎移植的價(jià)值。 方法：收集2012年1月—2013年1月在我院接受并完成第一周期長(zhǎng)方案IVF-ET治療的318個(gè)新鮮胚胎移植周期及2010年1月—2013年1月行凍融胚胎移植的667個(gè)周期不孕癥患者的臨床資料。以?xún)?yōu)質(zhì)胚胎組為對(duì)照組,非優(yōu)質(zhì)胚胎為研究組,比較新鮮移植周期及冷凍移植周期在周期臨床妊娠率、胚胎種植率、生化妊娠率、早期流產(chǎn)率、多胎率、宮外孕率及抱嬰率等指標(biāo)的差異。 結(jié)果：1.新鮮胚胎移植周期中,優(yōu)質(zhì)胚胎的臨床妊娠率高于非優(yōu)質(zhì)胚胎組。非優(yōu)質(zhì)胚胎的臨床妊娠率隨著胚胎移植數(shù)目的增加而增加，移植3個(gè)胚胎時(shí)，其臨床妊娠率接近優(yōu)質(zhì)胚胎組(分別為43.6%和44.0%)(p＞0.05)。2.凍融胚胎移植中,冷凍前后均為優(yōu)質(zhì)胚胎的臨床妊娠率高于非優(yōu)質(zhì)胚胎組。未受損的非優(yōu)質(zhì)的臨床妊娠率隨胚胎移植數(shù)目的增加而增加。胚胎凍融后發(fā)生部分冷凍受損的胚胎臨床妊娠率最低，增加冷凍損傷胚胎的移植數(shù)目并不能提高臨床妊娠率。 結(jié)論：1.在新鮮胚胎移植周期中，當(dāng)無(wú)優(yōu)質(zhì)胚胎時(shí)，移植非優(yōu)質(zhì)胚胎也有較好的成功率，，可以使用，不應(yīng)放棄。2.非優(yōu)質(zhì)胚胎凍融復(fù)蘇后，應(yīng)選擇卵裂球完好胚胎移植，放棄有破損的胚胎。
[Abstract]:Objective: to study the value of non-high quality embryo transfer by analyzing the data of fresh and frozen transfer cycles. Methods: the clinical data of 318 fresh embryo transfer cycles received and completed the first long term IVF-ET treatment in our hospital from January 2012 to January 2013 and 667 cycles of infertility patients undergoing frozen and thawed embryo transfer from January 2010 to January 2013 were collected. To compare the clinical pregnancy rate, embryo implantation rate, biochemistry pregnancy rate, early abortion rate, multiple pregnancy rate between fresh and frozen transfer cycles, the control group was used as the control group and the non-high quality embryo group as the study group. The difference of ectopic pregnancy rate and infantile rate. The result is 1: 1. The clinical pregnancy rate of high-quality embryos was higher than that of non-high-quality embryos in the fresh embryo transfer cycle. The clinical pregnancy rate of non-high quality embryos increased with the increase of the number of embryo transfer. When 3 embryos were transferred, the clinical pregnancy rate was close to that of the high quality embryo group (43.6% and 44.0%) (p > 0. 05). The clinical pregnancy rate of frozen and thawed embryos before and after freezing was higher than that of non-quality embryos. Undamaged non-quality clinical pregnancy rates increase with the number of embryo transplants. The clinical pregnancy rate of partially frozen damaged embryos after freeze-thawing was the lowest, and increasing the number of frozen damaged embryos could not improve the clinical pregnancy rate. Conclusion 1. In the fresh embryo transfer cycle, when there is no high-quality embryo, the transfer of non-high quality embryos also has a better success rate, can be used, should not give up. 2. After freeze-thaw resuscitation, cleavage ball should be selected for intact embryo transfer, and damaged embryo should be abandoned.
【學(xué)位授予單位】：遵義醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R714.8

【參考文獻(xiàn)】

相關(guān)期刊論文 前5條

1 陳士嶺;李勁;孫玲;邢福祺;;取卵后第3天胚胎形態(tài)學(xué)指標(biāo)與移植后著床的關(guān)系[J];實(shí)用婦產(chǎn)科雜志;2007年02期

2 王賀;李蓉;郝桂琴;;體外受精-胚胎移植周期中第3天移植胚胎細(xì)胞數(shù)與妊娠率的相關(guān)性[J];生殖醫(yī)學(xué)雜志;2007年04期

3 何馳華;皮潔;朱敬香;;睪丸取精卵胞漿內(nèi)單精子注射術(shù)后第3天移植四細(xì)胞胚胎獲妊娠一例[J];生殖醫(yī)學(xué)雜志;2008年06期

4 劉風(fēng)華;何玲;;輔助生殖技術(shù)出生兒近期安全性評(píng)價(jià)[J];現(xiàn)代婦產(chǎn)科進(jìn)展;2010年03期

5 戴善軍;孫瑩璞;蘇迎春;郭藝紅;辛志敏;金海霞;;體外受精非優(yōu)質(zhì)胚胎凍融的臨床價(jià)值[J];徐州醫(yī)學(xué)院學(xué)報(bào);2007年04期

本文編號(hào)：2154360