【摘要】：目的觀察阿托西班與利托君治療高齡孕婦先兆早產(chǎn)的效果及圍生兒結(jié)局。方法接受保胎治療的先兆早產(chǎn)孕婦199例,根據(jù)孕婦年齡及應(yīng)用的保胎藥物不同分為高齡(年齡≥35歲)阿托西班組(A組)47例、適齡(20歲年齡35歲)阿托西班組(B組)52例、高齡利托君組(C組)50例、適齡利托君組(D組)50例,比較各組治療效果效果、不良反應(yīng)及圍生兒結(jié)局。結(jié)果 1A組48 h有效率、7 d有效率及圍生兒結(jié)局不及B組,兩組相比,P均0.05;A、B組兩組不良反應(yīng)發(fā)生率相比,P0.05。2A、C組孕婦不良反應(yīng)發(fā)生率相比,P0.05;但A、C組48 h和7 d有效率、圍生兒結(jié)局相比,P0.05。3C組48 h和7 d有效率低于D組,其不良反應(yīng)發(fā)生率、新生兒窒息率及圍生兒死亡率高于D組,兩組相比,P均0.05。結(jié)論阿托西班與利托君治療高齡孕婦先兆早產(chǎn)的保胎效果、圍生兒結(jié)局相近,但兩種藥物對(duì)高齡孕婦先兆早產(chǎn)的保胎效果、圍產(chǎn)兒結(jié)局均差于適齡孕婦先兆早產(chǎn),高齡孕婦應(yīng)用阿托西班的安全性好于利托君。
[Abstract]:Objective to observe the effect and perinatal outcome of atoxiban and litojun in the treatment of threatened premature delivery of elderly pregnant women. Methods 199 pregnant women with threatened preterm delivery who received fetal preservation therapy were divided into four groups according to the age of the pregnant women and the antifetal drugs used. According to the age of the pregnant women, 47 cases were in the atossiban group (age 鈮，

本文編號(hào)：2128481