孕婦血栓彈力圖正常值參考范圍的建立
發(fā)布時間：2018-07-14 16:18
【摘要】：目的建立評價孕婦凝血功能血栓彈力圖(TEG)正常值參考范圍。方法按照懷孕與否與體檢結果將166名孕婦和64名未孕健康婦女分別納入懷孕組和非懷孕(對照)組,檢測其TEG值、傳統(tǒng)凝血指標值;分析比較2組婦女TEG各參數,對存在差異的參數建立參考值范圍。進一步分析足月妊娠對TEG結果的影響;對孕婦傳統(tǒng)凝血指標與TEG檢測結果做相關性分析。結果孕婦和健康未孕婦女的傳統(tǒng)凝血指標和TEG檢測結果存在明顯不同,根據結果建立的新的TEG參考范圍:R 3.9-7.5 min,K 1.0-2.4 min,α57.6°-74.9°,MA 55.7-75.7 mm,LY30 0-0.56%,CI(-0.97)-3.6。足月妊娠對TEG結果無明顯影響。除LY30外,孕婦TEG其他參數均與傳統(tǒng)凝血指標具有一定的相關性。結論一般人群的TEG參考值范圍不適用于孕婦;建立起的孕婦TEG正常值參考范圍可應用于臨床。
[Abstract]:Objective to establish a reference range for evaluating the normal value of thromboelastography (TEG) in pregnant women. Methods 166 pregnant women and 64 non-pregnant healthy women were divided into pregnancy group and non-pregnant (control) group according to the results of pregnancy and physical examination, the TEG value and the traditional coagulation index value were measured, and the parameters of TEG were analyzed and compared between the two groups. Establish a range of reference values for different parameters. The effect of term pregnancy on the results of TEG was further analyzed, and the correlation between the traditional coagulation parameters and the results of TEG was analyzed. Results there were significant differences between the traditional coagulation indexes and the test results of TEG in pregnant women and healthy non-pregnant women. According to the results, a new reference range of TEG: 1: R 3.9-7.5 min K 1.0-2.4 min, 偽 57.6 擄-74.9 擄MA 55.7-75.7 mm LY30 0-0.56 CI (-0.97) -3.6 was established. Term pregnancy had no significant effect on the outcome of TEG. With the exception of LY30, the other parameters of TEG in pregnant women were correlated with the traditional coagulation parameters. Conclusion the reference range of TEG in general population is not suitable for pregnant women, and the normal reference range of TEG for pregnant women can be used in clinic.
【作者單位】： 中南大學湘雅三醫(yī)院輸血科;
【基金】：中南大學研究生自主探索創(chuàng)新項目(2017zzts835)
【分類號】：R714.1
本文編號：2122216
[Abstract]:Objective to establish a reference range for evaluating the normal value of thromboelastography (TEG) in pregnant women. Methods 166 pregnant women and 64 non-pregnant healthy women were divided into pregnancy group and non-pregnant (control) group according to the results of pregnancy and physical examination, the TEG value and the traditional coagulation index value were measured, and the parameters of TEG were analyzed and compared between the two groups. Establish a range of reference values for different parameters. The effect of term pregnancy on the results of TEG was further analyzed, and the correlation between the traditional coagulation parameters and the results of TEG was analyzed. Results there were significant differences between the traditional coagulation indexes and the test results of TEG in pregnant women and healthy non-pregnant women. According to the results, a new reference range of TEG: 1: R 3.9-7.5 min K 1.0-2.4 min, 偽 57.6 擄-74.9 擄MA 55.7-75.7 mm LY30 0-0.56 CI (-0.97) -3.6 was established. Term pregnancy had no significant effect on the outcome of TEG. With the exception of LY30, the other parameters of TEG in pregnant women were correlated with the traditional coagulation parameters. Conclusion the reference range of TEG in general population is not suitable for pregnant women, and the normal reference range of TEG for pregnant women can be used in clinic.
【作者單位】： 中南大學湘雅三醫(yī)院輸血科;
【基金】：中南大學研究生自主探索創(chuàng)新項目(2017zzts835)
【分類號】：R714.1
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