本文選題：子癇前期 + sFlt-��； 參考：《齊齊哈爾醫(yī)學(xué)院學(xué)報》2015年35期

【摘要】：目的研究sFlt-1、PLGF和sEng水平表達(dá)情況,以及它們與子癇前期的相關(guān)性;分析子癇前期與氧化應(yīng)激、炎癥機制的相關(guān)性。方法檢測正常孕婦組、輕度子癇前期組、重度子癇前期組血樣標(biāo)本中的sFlt-1、PLGF、sEng及CRP的含量。結(jié)果重度PE患者的sFlt-1水平高于正常孕婦和輕度PE患者,而且差異均有統(tǒng)計學(xué)意義(q=10.64,8.10,P0.01);正常孕婦的PLGF水平高于輕度PE患者和重度PE患者,而且差異均有統(tǒng)計學(xué)意義(q=5.84,10.51,P0.01);正常孕婦的sEng水平低于輕度PE患者和重度PE患者,而且差異均有統(tǒng)計學(xué)意義(q=9.38,28.41,P0.01);正常孕婦的CRP水平低于輕度PE患者和重度PE患者,而且差異均有統(tǒng)計學(xué)意義(q=12.88,18.04,P0.01)。結(jié)論sFlt-1,PLGF,sEng可以用于子癇前期病的診斷,且可以反應(yīng)病情進(jìn)展,聯(lián)合監(jiān)測優(yōu)于單一監(jiān)測。
[Abstract]:Objective to study the expression of sFlt-1 PLGF and sEng and their correlation with preeclampsia, and to analyze the relationship between preeclampsia and oxidative stress and inflammatory mechanism. Methods the levels of serum sFlt-1 PLGFGF-sEng and CRP in normal pregnant women, mild preeclampsia and severe preeclampsia were detected. Results the levels of sFlt-1 in patients with severe PE were higher than those in normal women and mild patients with PE, and the differences were statistically significant (qP0.01), and the levels of PLGF in normal pregnant women were higher than those in patients with mild PE and those with severe PE (P 0.01). The levels of sEng in normal pregnant women were lower than those in mild PE patients and severe PE patients, and the differences were statistically significant (q9.38c28.41g P0.01), while the CRP levels of normal pregnant women were lower than those of mild PE patients and severe PE patients (P 0.01), and the levels of CRP in normal pregnant women were lower than those in mild PE patients and severe PE patients (P 0.01), and the levels of CRP in normal pregnant women were significantly lower than those in mild PE patients and severe PE patients. And the difference was statistically significant (QR 12.88, 18.04, P0.01). Conclusion sFlt-1 PLGFGF-sEng can be used in the diagnosis of preeclampsia and can reflect the progress of the disease, and the combined monitoring is better than the single monitoring.
【作者單位】： 鹽城市婦幼保健院;蘇州大學(xué)附屬第一人民醫(yī)院;
【分類號】：R714.244

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 桑翠琴;張震宇;王淑珍;劉浩;郭淑麗;;重度子癇前期/子癇合并急性呼吸窘迫綜合征的診斷與處理[J];中國醫(yī)刊;2006年10期

2 趙桂花;;重度子癇前期與子癇82例臨床分析[J];臨床醫(yī)藥實踐雜志;2007年01期

3 楊小頎;嚴(yán)妮子;;子癇前期與血鈣水平相關(guān)性研究[J];實用臨床醫(yī)學(xué);2007年04期

4 楊小頎;嚴(yán)妮子;;子癇前期與血鈣水平相關(guān)性研究[J];四川生理科學(xué)雜志;2007年01期

5 陳茜;王澤華;;子癇前期的預(yù)測及預(yù)防[J];華中醫(yī)學(xué)雜志;2007年03期

6 朱倩;;對38例子癇前期(重)、子癇治愈的體會[J];實用預(yù)防醫(yī)學(xué);2007年05期

7 梁英;周麗麗;甘娟;姜碧洋;楊承東;;重度子癇前期在產(chǎn)科ICU監(jiān)護(hù)救治的臨床分析[J];中國婦幼保健;2008年19期

8 詹衛(wèi)星;鄭九生;;血管緊張素轉(zhuǎn)換酶基因多態(tài)性與重度子癇前期及腎功能損害的關(guān)系[J];江西醫(yī)藥;2008年08期

9 蔡穎;尹國武;姜鋒;李怡;閔保華;王s，

本文編號：2117334