本文選題：卵巢交界性腫瘤 + 上皮性卵巢癌　； 參考：《大連醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的：比較卵巢交界性腫瘤與早期上皮性卵巢癌的臨床特點(diǎn)，鑒別存在于兩者間的高危因素，提高術(shù)前診斷率。 方法：收集大連醫(yī)科大學(xué)附屬婦產(chǎn)醫(yī)院從2008年1月到2012年12月因卵巢腫瘤而收入院的患者的診療記錄，經(jīng)術(shù)后病理明確診斷為卵巢交界性腫瘤或I期上皮性卵巢癌。其中：卵巢交界性腫瘤患者（BOT組）90例；I期上皮性卵巢癌患者（EOT組）72例。對(duì)兩組患者的一般情況、臨床表現(xiàn)、輔助檢查、手術(shù)及術(shù)后病理情況進(jìn)行對(duì)比分析。 結(jié)果：BOT組和EOC組發(fā)病的平均年齡為（41.10±10.11）歲和（53.61±7.25）歲，P=0.002，存在統(tǒng)計(jì)學(xué)差異；在未絕經(jīng)患者中，兩組的平均年齡為（38.16±7.56）歲和（45.67±4.61）歲，P=0.001，存在統(tǒng)計(jì)學(xué)差異；兩組間絕經(jīng)患者所占的比例也存在統(tǒng)計(jì)學(xué)差異；但在絕經(jīng)患者中，兩組的發(fā)病年齡沒(méi)有統(tǒng)計(jì)學(xué)差異。 兩組間腫瘤家族病史所占比例分別為1.11%、8.33%，P=0.025，存在統(tǒng)計(jì)學(xué)差異，在合并子宮內(nèi)膜異位癥、腫瘤發(fā)病位置及盆腔積液等情況中沒(méi)有統(tǒng)計(jì)學(xué)差異。 兩組中腫物實(shí)性部分大小的平均值分別為（29.00±14.80）mm vs.（47.20±33.56）mm，P=0.017，，存在統(tǒng)計(jì)學(xué)差異，但在腫物大小、實(shí)性部分比例、RI值等方面無(wú)統(tǒng)計(jì)學(xué)差異。 CEA在兩組間升高情況下的平均值分別為52.40ng/ml和7.73ng/ml，P0.001，存在統(tǒng)計(jì)學(xué)差異。而CA125與CEA的數(shù)值在兩組間及CA125在兩組間升高情況下的平均值均無(wú)統(tǒng)計(jì)學(xué)差異。 兩組間在術(shù)后病理類(lèi)型的分布上存在統(tǒng)計(jì)學(xué)差異(P0.001)。 結(jié)論：通過(guò)回顧性研究，比較卵巢交界性腫瘤與I期上皮性卵巢癌的臨床特點(diǎn)，就本研究而言，與早期上皮性卵巢癌相比，卵巢交界性腫瘤的患者在發(fā)病年齡、絕經(jīng)情況、腫瘤家族史、超聲提示腫物實(shí)性部分大小、腫瘤標(biāo)志物升高情況及病理類(lèi)型等方面均有所不同。
[Abstract]:Objective: to compare the clinical features of borderline ovarian tumor and early epithelial ovarian cancer, to differentiate the high risk factors between them and to improve the preoperative diagnosis rate. Methods: the records of diagnosis and treatment of patients admitted to Dalian Medical University affiliated Gynecology Hospital from January 2008 to December 2012 due to ovarian tumors were collected and diagnosed as borderline ovarian tumors or stage I epithelial ovarian cancer by postoperative pathology. There were 72 cases of epithelial ovarian cancer (EOT group) in 90 cases of ovarian borderline tumor (bot group). The general condition, clinical manifestation, auxiliary examination, operation and postoperative pathology of the two groups were compared and analyzed. Results the mean age of onset in the two groups was (41.10 鹵10.11) years and (53.61 鹵7.25) years old (P 0.002), and the mean age of the two groups was (38.16 鹵7.56) years old and (45.67 鹵4.61) years old (P 0.001). There was also a statistical difference in the proportion of menopausal patients between the two groups, but there was no significant difference in onset age between the two groups. The proportion of family history of tumor was 1.118.33 and 0.025 respectively between the two groups. There was no statistical difference between the two groups in the cases of endometriosis, location of tumor and pelvic effusion. The mean size of solid mass in the two groups was (29.00 鹵14.80) mm vs. (鹵47.20 鹵33.56) mmP0. 017 respectively, there was statistical difference between the two groups, but in the tumor size, There was no significant difference in RI value between the two groups, but the average value of 52.40ng/ml was 7.73 ng / ml / ml P 0.001 in the two groups respectively, and there was statistical difference between the two groups. However, there was no significant difference in the values of CA125 and CEA between the two groups and the mean values of CA125 in both groups. There was statistical difference in the distribution of postoperative pathological types between the two groups (P 0.001). Conclusion: the clinical characteristics of ovarian borderline tumor and stage I epithelial ovarian cancer were compared by retrospective study. In this study, the age of onset and menopause of borderline ovarian cancer were compared with those of early epithelial ovarian cancer. The family history of tumor, the size of solid tumor, the elevation of tumor markers and pathological types were different.
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類(lèi)號(hào)】：R737.31

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 糜若然,瞿全新;卵巢交界性瘤[J];中國(guó)實(shí)用婦科與產(chǎn)科雜志;2003年08期

本文編號(hào)：2054144