本文選題：宮頸癌 + 保留生育功能�。� 參考：《實(shí)用婦產(chǎn)科雜志》2015年04期

【摘要】：目的:比較改良腹式廣泛宮頸切除術(shù)(MART)與全腹腔鏡廣泛宮頸切除術(shù)(TLRT)在早期宮頸癌保留生育功能治療中的技術(shù)異同性、臨床治療效果和妊娠結(jié)局。方法:收集2002年10月至2014年7月46例早期宮頸癌并接受MART或TLRT手術(shù)患者的臨床資料和隨訪結(jié)果,并進(jìn)行對(duì)比。結(jié)果:46例患者均完成預(yù)期手術(shù),其中MART組27例,TLRT組19例。TLRT組術(shù)中出血量及住院時(shí)間明顯少于MART組(P0.05),MART組在手術(shù)時(shí)間、切除宮旁組織長(zhǎng)度、子宮動(dòng)脈損傷率方面明顯優(yōu)于TLRT組(P0.05)。兩組切除淋巴結(jié)數(shù)、腹腔引流量及膀胱功能障礙發(fā)生率等比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。術(shù)后隨訪兩組均無(wú)復(fù)發(fā),MART組妊娠率(38.10%)與TLRT組(53.85%)比較,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:MART和TLRT兩種手術(shù)方式均可有效治療早期宮頸癌并實(shí)現(xiàn)患者保留生育功能的愿望。MART術(shù)式切除宮旁范圍較TLRT相對(duì)較廣,TLRT在減少術(shù)中出血及對(duì)盆腔臟器的干擾方面有其微創(chuàng)的優(yōu)勢(shì)。選擇手術(shù)方式應(yīng)個(gè)體化。
[Abstract]:Objective: to compare the technical differences, clinical effects and pregnancy outcomes between modified abdominal extensive cervical resection (MARTT) and total laparoscopic extensive cervical resection (TLRT) in the treatment of early cervical cancer with fertility retention. Methods: the clinical data and follow-up results of 46 patients with early cervical cancer underwent Mart or TLRT from October 2002 to July 2014 were collected and compared. Results the expected operation was performed in all 46 patients. The blood loss and hospital stay in the TLRT group (n = 27) were significantly lower than those in the Mart group (P 0.05), the length of paracentric tissue and the rate of uterine artery injury were significantly better than those in the TLRT group. There was no significant difference in the number of lymph nodes, abdominal drainage and bladder dysfunction between the two groups (P 0.05). There was no significant difference in pregnancy rate between the two groups (38.10%) and TLRT group (53.85%). Conclusion both of the two methods can be effective in the treatment of early cervical cancer and realize the wish of preserving fertility function of patients. The paracentric resection of TLRT is more extensive than that of TLRT. TLRT can reduce intraoperative bleeding and interfere with pelvic organs. Has its minimally invasive advantage. The choice of operation should be individualized.
【作者單位】： 南方醫(yī)科大學(xué)珠江醫(yī)院;廣州醫(yī)學(xué)院第三附屬醫(yī)院;北京大學(xué)深圳醫(yī)院;中山大學(xué)附屬東華醫(yī)院;
【基金】：廣東省科學(xué)技術(shù)廳科技計(jì)劃資助項(xiàng)目(編號(hào):2005B36001017) 南方醫(yī)科大學(xué)珠江醫(yī)院人才引進(jìn)基金
【分類號(hào)】：R737.33

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 魯琦;張?jiān)弃Q;王淑珍;郭淑麗;劉崇東;張震宇;;腹腔鏡下廣泛子宮頸切除術(shù)治療早期子宮頸鱗狀細(xì)胞癌的初步研究[J];國(guó)際婦產(chǎn)科學(xué)雜志;2013年04期

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本文編號(hào)：2046599