本文選題：宮頸腫瘤 + TCT檢測��； 參考：《臨床合理用藥雜志》2016年36期

【摘要】：目的探討薄層液基細(xì)胞學(xué)檢測技術(shù)(TCT)、HPV-DNA分型聯(lián)合陰道鏡在宮頸癌篩選中的應(yīng)用價值。方法選取2014—2015年于靈丘縣婦幼保健院行宮頸檢查并診斷為宮頸病變的患者927例,均行TCT檢測、HPV-DNA分型檢測,并對859例高度懷疑為宮頸癌患者在陰道鏡下進(jìn)行宮頸活組織檢測、TCT檢測、HPV-DNA分型檢測及病理檢測,對比分析其檢查結(jié)果。結(jié)果 TCT檢測為正常或炎癥患者HPV-DNA分型檢測的陽性率低于TCT檢測為低度鱗狀上皮內(nèi)病變及高度鱗狀上皮內(nèi)病變(P0.05);TCT檢測為非典型鱗狀上皮細(xì)胞病變患者HPVDNA分型檢測的陽性率低于TCT檢測為高度鱗狀上皮內(nèi)病變及鱗狀細(xì)胞癌(P0.05)。TCT、HP-DNA分型檢測對病理學(xué)檢測結(jié)果為重度不典型增生及鱗狀細(xì)胞癌患者的陽性檢出率高于輕度、中度不典型增生(P0.05)。TCT、HPV-DNA及陰道鏡聯(lián)合對輕、中、中度不典型增生的準(zhǔn)確率高于TCT與HPV-DNA聯(lián)合(P0.05)。結(jié)論 TCT、HPV-DNA分型聯(lián)合陰道鏡在宮頸癌篩選中安全、高效,可降低漏診率。
[Abstract]:Objective to investigate the application value of TCTL HPV-DNA typing combined with colposcopy in screening cervical cancer. Methods from 2014 to 2015, 927 cases of cervical diseases were examined and diagnosed in Lingqiu County Maternal and Child Health Care Hospital. All of them were detected by TCT and HPV-DNA typing. HPV-DNA typing and pathological examination were performed in 859 highly suspected cervical cancer patients under colposcopy. The results were compared and analyzed. Results the positive rate of HPV-DNA typing in normal or inflammatory patients with TCT was lower than that in patients with low grade squamous intraepithelial lesions (LSCI) and high squamous intraepithelial lesions (HPVDNA). The positive rate of HP-DNA was lower than that of TCT in patients with high squamous intraepithelial lesions and squamous cell carcinoma. The positive rate of HP-DNA typing in patients with severe atypical hyperplasia and squamous cell carcinoma was higher than that in mild squamous cell carcinoma. The accuracy of HPV-DNA combined with colposcopy for mild and moderate dysplasia was higher than that of TCT combined with HPV-DNA. Conclusion TCTN HPV-DNA typing combined with colposcopy is safe and effective in screening cervical cancer and can reduce the rate of missed diagnosis.
【作者單位】： 山西省靈丘縣婦幼保健院;
【分類號】：R737.33

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