本文選題：宮頸疾病 + 液基細(xì)胞學(xué)　； 參考：《重慶醫(yī)學(xué)》2015年15期

【摘要】：目的探討液基薄層細(xì)胞學(xué)檢查(TCT)聯(lián)合DNA定量分析在宮頸病變篩查中的應(yīng)用價值。方法回顧性分析TCT(n=2 883)、DNA定量分析(n=1 742)及TCT聯(lián)合DNA定量分析(n=333)3種方法對診斷宮頸病變的臨床意義。結(jié)果TCT、DNA定量分析和聯(lián)合檢查的陽性符合率分別為43.86%、68.04%、81.16%,對宮頸上皮內(nèi)瘤變(CIN)Ⅰ及以上病變的診斷,TCT與DNA定量分析陽性符合率差異有統(tǒng)計學(xué)意義(P0.01),聯(lián)合檢查與DNA定量分析、TCT相比,陽性符合率差異均有統(tǒng)計學(xué)意義(P0.01)。TCT檢查發(fā)現(xiàn)宮頸病變的敏感性、特異性為69.44%、92.42%;DNA定量分析發(fā)現(xiàn)宮頸病變的敏感性、特異性為85.71%、87.89%;聯(lián)合檢查發(fā)現(xiàn)宮頸病變的敏感性、特異性為96.55%、95.89%。結(jié)論 DNA定量分析和TCT在宮頸病變篩查中均有較高的臨床診斷價值,聯(lián)合檢查更能有效地提高宮頸病變的檢出率。
[Abstract]:Objective to evaluate the value of liquid-based thin-layer cytology combined with quantitative analysis of DNA in screening cervical lesions. Methods the clinical significance of quantitative analysis of TCT(n=2 883 and TCT combined with DNA in the diagnosis of cervical lesions was analyzed retrospectively. Results the positive coincidence rates of quantitative analysis and combined examination were 43.86 and 68.04 and 81.16, respectively. The positive coincidence rates of TCT and DNA in the diagnosis of cervical intraepithelial neoplasia 鈪，

本文編號：1961801