本文選題：卵巢子宮內(nèi)膜異位癥 + 囊腫剔除　； 參考：《浙江大學(xué)》2017年碩士論文

【摘要】：目的:研究腹腔鏡下卵巢子宮內(nèi)膜異位囊腫剔除手術(shù)對(duì)卵巢儲(chǔ)備功能的影響。方法:選擇在我院接受腹腔鏡下卵巢囊腫剔除手術(shù)治療,術(shù)后病理診斷為卵巢子宮內(nèi)膜異位癥的患者共212例,比較手術(shù)前后卵巢激素水平的改變來(lái)探究腹腔鏡下卵巢子宮內(nèi)膜異位囊腫剔除手術(shù)對(duì)卵巢儲(chǔ)備功能的影響。結(jié)果:腹腔鏡下卵巢子宮內(nèi)膜異位囊腫剔除手術(shù)術(shù)后6個(gè)月內(nèi)血清FSH、FSH/LH較術(shù)前明顯上升,E2水平較術(shù)前明顯下降(P0.05);術(shù)后6個(gè)月以上FSH/LH較術(shù)前明顯上升,(P0.05),而血清FSH及E2水平較術(shù)前比較無(wú)明顯變化(P0.05)。單側(cè)卵巢子宮內(nèi)膜異位囊腫手術(shù)剔除后血清FSH及FSH/LH較術(shù)前顯著升高(P0.05),E2水平較術(shù)前明顯下降。雙側(cè)卵巢子宮內(nèi)膜異位囊腫手術(shù)剔除后血清FSH較術(shù)前差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),FSH/LH較術(shù)前顯著升高(P0.05),E2水平較術(shù)前明顯下降(P0.05)。單側(cè)卵巢子宮內(nèi)膜異位囊腫和雙側(cè)卵巢子宮內(nèi)膜異位囊腫相比較,在術(shù)前雙側(cè)卵巢囊腫FSH較單側(cè)囊腫高(P0.05),而FSH/LH及E2水平與單側(cè)卵巢囊腫無(wú)明顯差異(P0.05)。在術(shù)后雙側(cè)卵巢囊腫FSH及E2水平與單側(cè)卵巢囊腫無(wú)明顯差異(P0.05),而FSH/LH值較單側(cè)囊腫低(P0.05)。卵巢子宮內(nèi)膜異位囊腫直徑≤3cm,手術(shù)前后FSH、FSH/LH及E2水平無(wú)明顯差異(P0.05)。囊腫直徑3cmm且≤5cm,術(shù)后FSH及FSH/LH較術(shù)前明顯升高(P0.05),E2水平無(wú)明顯差異(P0.05)。囊腫直徑5cm,術(shù)后FSH及FSH/LH較術(shù)前明顯升高(P0.05),E2水平較術(shù)前明顯下降(P0.05)。結(jié)論:腹腔鏡下卵巢子宮內(nèi)膜異位囊腫剔除手術(shù)可能降低卵巢的儲(chǔ)備功能,尤其是在囊腫直徑較大時(shí),但這種影響多能在半年后恢復(fù)。
[Abstract]:Objective: to study the effect of laparoscopic ovarian endometriosis cystectomy on ovarian reserve function. Methods: a total of 212 patients with ovarian endometriosis were treated by laparoscopic ovarian cyst excision and pathologically diagnosed as ovarian endometriosis. To investigate the effect of laparoscopic ovarian endometriosis cystectomy on ovarian reserve function by comparing the changes of ovarian hormone levels before and after surgery. Results: the serum levels of FSHF / FSH / LH increased significantly within 6 months after laparoscopic ovarian endometriosis cystectomy. The level of E2 decreased significantly compared with that before operation, and the level of FSH/LH increased significantly over 6 months after operation. The serum levels of FSH and E2 were significantly higher than those before operation. There was no significant change in the level of P0.05 compared with that before operation. The levels of serum FSH and FSH/LH in patients with unilateral ovarian endometriosis were significantly higher than those before operation. There was no significant difference in serum FSH after resection of bilateral ovarian endometriosis cysts. The level of serum P0.05FSH / LH was significantly higher than that of preoperation and the level of P0.05FSH / LH was significantly lower than that of preoperation. Compared with unilateral ovarian endometriosis cysts and bilateral ovarian endometriosis cysts, the FSH of bilateral ovarian cysts was higher than that of unilateral ovarian cysts before operation, while the levels of FSH/LH and E2 were not significantly different from those of unilateral ovarian cysts. The levels of FSH and E2 in bilateral ovarian cysts were not significantly different from those in unilateral ovarian cysts (P 0.05), but the FSH/LH values were lower than those in unilateral cysts (P 0.05). The diameter of ovarian endometriosis cyst was less than 3 cm. There was no significant difference in FSH / LH and E2 levels before and after operation. The diameter of cyst 3cmm was less than 5 cm. There was no significant difference in the level of P0.05 and E2 between FSH and FSH/LH after operation. The diameter of cysts was 5 cm, and the levels of FSH and FSH/LH were significantly higher than those before operation. Conclusion: laparoscopic resection of ovarian endometriosis cysts may reduce ovarian reserve function, especially when the diameter of cyst is larger, but this effect can be recovered in half a year.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R713.6
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本文編號(hào)：1947618