本文選題：腎虛肝郁 + 早期先兆流產(chǎn)�。� 參考：《山東中醫(yī)藥大學(xué)》2016年碩士論文

【摘要】：目的:本文主要通過對早期先兆流產(chǎn)的治療現(xiàn)狀及相關(guān)臨床病例研究,探討自擬補腎疏肝湯結(jié)合西藥治療早期先兆流產(chǎn)的臨床綜合療效,以期利用中醫(yī)藥治療早期先兆流產(chǎn)的優(yōu)勢和特色,將該種治療方法更多地應(yīng)用到以后臨床保胎工作中。方法:將符合妊娠早期腎虛肝郁型先兆流產(chǎn)診斷標(biāo)準(zhǔn)的68例患者,隨機分為治療組與對照組兩組,治療組患者口服中藥自擬補腎疏肝湯并結(jié)合西藥肌肉注射黃體酮注射液;對照組患者僅用西藥肌肉注射黃體酮注射液。每7天為一個療程,連續(xù)治療2個療程后觀察兩組患者臨床癥狀的改善情況、血清激素水平(孕酮、人絨毛膜促性腺激素、雌二醇)及B超監(jiān)測妊娠囊的生長的檢驗結(jié)果,綜合分析其結(jié)果對兩組臨床療效的影響。結(jié)果:治療組34例患者,總有效率94.12%,痊愈8例(23.53%),顯效17例(50.00%),有效7例(20.59%),無效2例(0.06%);對照組34例患者,總有效率82.35%,痊愈5例(14.71%),顯效8例(23.53%),有效15例(44.12%),無效6例(17.65%)。中西藥聯(lián)合用藥的治療組臨床療效明顯優(yōu)于單純西藥治療的對照組(P0.05),且治療組接受治療后的血清孕酮(P)、血清絨毛膜促性腺激素(β-HCG)及血清雌二醇(E2)比用藥前有明顯的提高,妊娠囊比用藥前明顯有生長。結(jié)論:自擬補腎疏肝湯聯(lián)合黃體酮治療腎虛肝郁型早期先兆流產(chǎn)療效明顯優(yōu)于臨床單獨應(yīng)用黃體酮,具體表現(xiàn)在改善孕期臨床癥狀、提高血清P、β-HCG、E2水平和胎兒在宮內(nèi)正常發(fā)育情況及臨床療效評價方面。因此中西醫(yī)結(jié)合治療早期先兆流產(chǎn)能陪同保護患者安全順利度過妊娠期。
[Abstract]:Objective: to explore the clinical comprehensive effect of Bushen Shugan decoction combined with western medicine in the treatment of early threatened abortion. In order to make use of the advantages and characteristics of Chinese medicine to treat early threatened abortion, this treatment method will be applied more to the later clinical fetal preservation work. Methods: 68 cases of threatened abortion with kidney deficiency and liver depression in early pregnancy were randomly divided into two groups: the treatment group and the control group. The patients in the treatment group were treated by oral Chinese medicine Bushen Shugan decoction combined with western medicine intramuscular injection of progesterone injection. Patients in the control group were treated by intramuscular injection of progesterone. The improvement of clinical symptoms, serum hormone levels (progesterone, human chorionic gonadotropin, estradiol) and B-ultrasound monitoring of the growth of pregnancy sac were observed after two consecutive courses of treatment. Comprehensive analysis of the results of the two groups of clinical efficacy. Results: in the treatment group, the total effective rate was 94.12. The cure rate was 23.53 in 8 patients, the significant effect was 50.005 in 17 patients, the effective rate was 20.599.59 in 7 patients, the ineffective in 2 patients was 0.060.The total effective rate was 82.35 in the control group, the total effective rate was 82.35, the cure rate was 14.71, the significant effect was 23.535.The effective rate was 44.12, and the ineffective was 17.656.The total effective rate was 82.35 in the control group. The clinical efficacy of the combined treatment group was significantly better than that of the control group (P 0.05), and the serum progesterone, chorionic gonadotropin (尾 -HCG) and serum estradiol E _ 2 (E _ 2) of the treatment group were significantly higher than those of the control group. The pregnancy sac grew more obviously than before. Conclusion: the effect of Bushen Shugan decoction combined with progesterone in the treatment of early threatened abortion with kidney deficiency and liver depression is better than that of progesterone alone, which is manifested in the improvement of clinical symptoms during pregnancy. To improve the level of serum P- 尾 -HCGG E 2 and the normal development of fetus in uterus and the evaluation of clinical curative effect. Therefore, integrated Chinese and western medicine treatment of early threatened abortion can be accompanied to protect the patient safely and smoothly through pregnancy.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R714.21

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