本文選題：卵巢 + 年齡��； 參考：《南昌大學》2014年碩士論文

【摘要】：目的： 1．探討三維超聲評估健康生育年齡婦女卵巢隨年齡的變化。 2．探討應用三維超聲導出各年齡組健康生育年齡婦女的三維卵巢數(shù)據(jù)。 3．探討二維超聲與三維超聲評估卵巢數(shù)據(jù)的相關(guān)性。 方法： 選取248名18-39歲月經(jīng)周期規(guī)則、經(jīng)期正常且月經(jīng)為自發(fā)性，無婦產(chǎn)科疾患癥狀及不孕不育病史婦女，按年齡將受試者分為四個組，18-24歲，25-29歲，30-34歲，35-39歲。測量受試者的身高、體重、血壓并在月經(jīng)的第3-5天即卵泡早期用經(jīng)陰道容積探頭行超聲檢測，包括常規(guī)二維灰階和彩色多普勒及三維灰階和三維能量多普勒掃描。二維超聲掃描子宮及雙側(cè)附件區(qū)排除婦產(chǎn)科疾病及卵巢黃體、卵巢囊腫等后測量雙側(cè)卵巢的體積、實時計算雙側(cè)卵巢竇卵泡的數(shù)量、最大卵泡的大小。二維完成后采集三維灰階和能量多普勒數(shù)據(jù)，使用軟件后處理并計算卵巢數(shù)據(jù)。包括最大卵泡的大小，總卵泡和卵巢的體積，竇卵泡的數(shù)量，卵巢的血管血流信息。卵巢的血管血流信息包括血管指數(shù)、血流指數(shù)及血管化血流指數(shù)。對上述數(shù)據(jù)進行統(tǒng)計學處理分析。 結(jié)果： 248人中有198人符合研究條件，被包括在最后的結(jié)果中。 四個年齡組間卵巢體積、竇卵泡的數(shù)量、總卵泡體積差異明顯，有顯著統(tǒng)計學意義（P0.001），雙側(cè)卵巢竇卵泡的數(shù)量、總卵泡體積、卵巢大小隨年齡的增加而有顯著的減少。雙側(cè)卵巢的最大卵泡的大小在各年齡組間差異沒有統(tǒng)計學意義。雙側(cè)卵巢的三維血管血流數(shù)據(jù)在各個年齡組間差異沒有統(tǒng)計學意義。二維實時測量的卵巢體積比三維VOCAL軟件測量的卵巢體積小，三維軟件SonoAVC自動計數(shù)的竇卵泡數(shù)量要少于二維竇卵泡的計數(shù),二維最大卵泡測量比三維SonoAVC軟件測量的數(shù)據(jù)要大。 18-24歲正常生育年齡婦女竇卵泡數(shù)量的Median (range)為23（10-58），25-29歲組的竇卵泡數(shù)量為21（11-50），30-34歲組的竇卵泡數(shù)量為18（5-38），35-39歲組的竇卵泡數(shù)量為12（2-20），竇卵泡數(shù)量在18-24歲組和25-29歲組間差異不明顯（P=0.258）。18-24歲正常生育年齡婦女總卵巢體積的Median (range)為13.9（6.8-29.7)cm3，，25-29歲組總卵巢體積為13.7（6.3-29.3）cm3，30-34歲組的總卵巢體積為12.7（5.0-25.3）cm3，35-39歲組的總卵巢體積為10.4（4.2-23.6）cm3，25-29歲組和18-24歲組間卵巢體積數(shù)據(jù)差異沒有統(tǒng)計學意義（P=0.440）。18-24歲正常生育年齡婦女總卵泡體積的Median (range)為2.05（0.32-3.81）cm3，25-29歲組總卵泡體積為1.93（0.29-3.69）cm3，30-34歲組的總卵泡體積為1.59（0.18-3.02）cm3，35-39歲組的總卵泡體積為1.28（0.12-2.30）cm3，25-29歲組和18-24歲組間竇卵泡體積數(shù)據(jù)差異沒有統(tǒng)計學意義（P=0.553）。 結(jié)論： 健康無婦產(chǎn)科疾病癥狀生育年齡婦女的雙側(cè)卵巢體積、竇卵泡的計數(shù)、總卵泡體積值均隨年齡的增加而呈明顯下降趨勢。各年齡組間雙側(cè)卵巢的三維血管血流指數(shù)差異沒有統(tǒng)計學意義。
[Abstract]:Objective: 1. Objective: to evaluate the changes of ovary with age in healthy women of reproductive age by three-dimensional ultrasound. 2. Objective: to study the three-dimensional ovarian data of healthy women of childbearing age in different age groups by three-dimensional ultrasound. 3. To investigate the correlation between two-dimensional ultrasound and three-dimensional ultrasound in evaluating ovarian data. Methods: 248 women aged 18-39 years with normal menstrual cycle and spontaneous menstruation without symptoms of gynecologic diseases and infertility were divided into four groups according to their ages: 18-24 years old, 25-29 years old, 30-34 years old and 35-39 years old. The height, weight, blood pressure of the subjects were measured by transvaginal volume probe during the 3-5 days of menstruation, including routine two-dimensional gray scale and color Doppler and three-dimensional gray scale and three-dimensional power Doppler scanning. The volume of bilateral ovaries was measured after the uterus and bilateral adnexal region were excluded from obstetrical and gynecological diseases, ovarian corpus luteum and ovarian cyst. The number of antral follicles and the size of the largest follicles were calculated in real time. Three dimensional grayscale and energy Doppler data were collected after 2 D, and ovary data were processed and calculated by software. These include the size of the largest follicle, the volume of the total follicle and ovary, the number of antral follicles, and the blood flow information of the ovaries. The blood flow information of ovary includes vascular index, blood flow index and vascularized blood flow index. The above data were analyzed statistically. Results: Of the 248, 198 were eligible for the study and included in the final results. There were significant differences in ovarian volume, number of antral follicles and total follicle volume among the four age groups (P 0.001). The number of antral follicles, total follicular volume and ovarian size decreased with age. There was no significant difference in the size of the largest follicles in the bilateral ovaries between different age groups. The three-dimensional blood flow data of bilateral ovaries had no significant difference among different age groups. The volume of ovaries measured by two-dimensional real-time measurement was smaller than that measured by three-dimensional VOCAL software. The number of antral follicles measured automatically by SonoAVC software was less than that by two-dimensional antral follicles, and the measurement of two-dimensional largest follicles was larger than that measured by three-dimensional SonoAVC software. The number of antral follicles of 18-24 years old women with normal reproductive age was 2310 ~ (-58) / 25 ~ 29 years old. The number of antral follicles in the 30-34 age group was 185-38 / 35 ~ 39 years old, and the number of antral follicles was 12 ~ 2 ~ 20 ~ 20%. There was no significant difference in the number of antral follicles between 18-24 years old group and 25-29 years old group. 18-24 years old group had no significant difference in the number of antral follicles between 18-24 years old group and 25-29 years old group. The number of antral follicles in 30-34 years old group was 185-38%. The total ovarian volume of women aged 30 to 34 years old in normal reproductive age group was 12.7V 5.0-25.3cm ~ (35) ~ 39 years old, the total ovarian volume was 10.44.2-23.6 cm ~ (-3) cm ~ (29) and 18-24 years old, there was no significant difference in the total ovarian volume between the age group and the 18-24 age group, the total ovarian volume of the women of normal reproductive age was 13.9C 6.8-29.7g 路cm ~ (3) ~ (-1) ~ (25 ~ 29). There was no significant difference in the total ovarian volume between the age group and the 18-24 age group. The total follicle volume of normal fertile age women aged 18-24 years was 2.05 ~ 0.32-3.81g / cm ~ (3) and the total follicle volume of 25-29 years old group was 1.93 ~ (0.29-3.69) cm ~ (3) C ~ (-1) = 1.590.18-3.02cm ~ (335-39). There was no significant difference in total follicular volume between the age group (1.28) 0.12-2.30 cm ~ (325-29) and the group of 18-24 years old (P _ (0.553N). Conclusion: The bilateral ovarian volume, antral follicle count and total follicle volume of healthy women of childbearing age without symptoms of gynecology and obstetrics disease showed an obvious decreasing trend with the increase of age. There was no significant difference in three-dimensional vascular blood flow index between different age groups.
【學位授予單位】：南昌大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R445.1;R711

【參考文獻】

相關(guān)期刊論文 前10條

1 葉璐;劉宏偉;;超聲檢查對卵巢儲備功能的評價及臨床意義[J];實用婦產(chǎn)科雜志;2013年09期

2 梁詩瑩;趙萍;;卵巢儲備功能的超聲研究進展[J];中華醫(yī)學超聲雜志(電子版);2013年08期

3 何淑明;梁麗霞;;育齡期婦女陰道彩色多普勒參數(shù)與卵巢儲備功能的關(guān)系[J];廣東醫(yī)學;2013年10期

4 周禮蘭;李瑛;;多囊卵巢綜合征診斷與治療的新進展[J];醫(yī)學綜述;2012年08期

5 陳士嶺;羅燕群;夏容;王樂樂;吳雅琴;;女性年齡與不孕及生育力減退[J];國際生殖健康/計劃生育雜志;2011年04期

6 王偉群;張華;蔡款;梁偉翔;嚴寶妹;朱s

本文編號：1892219