本文選題：宮頸癌 + 維吾爾族��； 參考：《新疆醫(yī)科大學(xué)》2014年碩士論文

【摘要】：目的：通過對新疆墨玉縣維吾爾族婦女宮頸組織病理診斷≥CIN Ⅱ的發(fā)病高危因素的分析并了解其高危人群,為宮頸病變的防治提供理論依據(jù)。方法：根據(jù)墨玉縣地理位置、人口分布、經(jīng)濟(jì)狀況,抽取4個鄉(xiāng)1個鎮(zhèn)21-60歲的已婚婦女5000人作為調(diào)查對象,自2013年5月15日至2013年9月15日期間,采用訪談方式進(jìn)行婦女基本信息的問卷調(diào)查、婦科檢查、care HPV檢測、TCT檢測,care HPV陽性、TCT結(jié)果為ASCUS及以上病變和AGC者行陰道鏡下宮頸活檢,對病理結(jié)果CIN Ⅱ以上(包括CINⅡ和CGIN)婦女的年齡、生活習(xí)慣、婚育史、初次性交年齡等資料進(jìn)行單因素、多因素的統(tǒng)計分析。結(jié)果：(1)5000個婦女中,HPV陽性者421人,檢出率8.4%；其中45歲以上的婦女HPV陽性率較高,TCT陽性者(為ASCUS以上者,包括ASCUS和AGC)222人,檢出率4.4%；HPV與TCT任意一個陽性者為545人,檢出率10.9%。(2)單因素分析結(jié)果顯示,婦女的年齡、HPV感染、結(jié)婚次數(shù)與CIN的發(fā)生之間的關(guān)聯(lián)有統(tǒng)計學(xué)差異,HPV感染、年齡的增長、結(jié)婚次數(shù)的增多會增加發(fā)生宮頸病變的可能性。(3)多因素分析結(jié)果,婦女的年齡、HPV感染與≥CINⅡ均有統(tǒng)計學(xué)意義。結(jié)論：(1)本項研究顯示,45歲以上的婦女HPV和宮頸病變的檢出率均較高,高危型HPV陽性的婦女,需警惕子宮頸癌前病變甚至是宮頸癌的存在。(2)年齡和HPV感染是維吾爾族婦女患≥CINⅡ級的高危因素,這部分人群應(yīng)作為重點篩查人群。
[Abstract]:Objective: to provide a theoretical basis for the prevention and treatment of cervical lesions through the analysis of the high risk factors for the pathological diagnosis of the cervical tissue of Uygur women in the Xinjiang Moyu County, which is more than CIN II, and to provide a theoretical basis for the prevention and treatment of cervical lesions. Methods: according to the geographical location, population distribution and economic status of the Moyu County, 5000 married women of 21-60 years old in 1 towns of 4 townships were selected as the basis. For the survey, from May 15, 2013 to September 15, 2013, questionnaires were conducted on basic information of women, gynecologic examination, care HPV test, TCT test, care HPV positive, TCT results for ASCUS and above pathological changes and cervical biopsy under colposcopy for AGC, and the pathological results were above CIN II (CIN II and CGIN) women. The data of age, life habit, marriage and breeding history and the age of first sexual intercourse were analyzed. Results: (1) among 5000 women, 421 were HPV positive, and the detection rate was 8.4%; among them, the positive rate of HPV was higher in women over 45 years of age, and 222 of TCT positive (above ASCUS, including ASCUS and AGC), 4.4%, HPV and TCT The positive rate was 545, and the detection rate of 10.9%. (2) single factor analysis showed that there were statistical differences between women's age, HPV infection, marriage times and the occurrence of CIN. HPV infection, age, marriage times increased the availability of cervical lesions. (3) multifactor analysis, women's age, HPV infection and > C IN II all have statistical significance. Conclusions: (1) this study showed that the detection rate of HPV and cervical lesions in women over the age of 45 years old was higher, and the women with high risk type HPV positive should be alert to the existence of cervical precancerous lesions and even cervical cancer. (2) age and HPV infection are the high risk factors for the Uygur women with CIN grade II. This part of the population should be made. To focus on screening people.

【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R737.33

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