本文選題：硅膠仿子宮體模 + 左炔諾孕酮�。� 參考：《遵義醫(yī)學院學報》2017年02期

【摘要】：目的建立一種硅膠仿子宮體模,用于評價左炔諾孕酮(LNG)彌散規(guī)律。方法以硅膠為主體成分制成仿子宮體模,把左炔諾孕酮置入其體腔中。將體模置于37℃恒溫箱中30、60 d后,以10 mm為間距分別于兩側(cè)壁切片。取15 g的切片置于無水乙醇溶液中,24 h后測量該溶液中LNG的吸光度。結(jié)果硅膠仿子宮體模完全透明,質(zhì)地均勻。放置仿子宮透明體模30、60 d后切片,各組所含LNG濃度的兩兩比較均有統(tǒng)計學意義(P0.01)。LNG在硅膠仿子宮體模的濃度隨體腔內(nèi)壁距離的增加呈遞減趨勢,其衰減符合線性規(guī)律。結(jié)論硅膠仿子宮體模的建立和LNG在體模壁中的濃度梯度現(xiàn)象,為LNG宮內(nèi)放置治療某些婦科疾病提供了理論依據(jù)。
[Abstract]:Objective to establish a silica gel imitating uterine body model to evaluate the dispersion of levonorgestrel (LNG). Method the silicone model was used as the main body to make a model of the uterus, and left progestonone was placed in the body cavity. After the body was placed in the 37 centigrade thermostat 30,60 D, 10 mm was separated into the two sides of the wall, and 15 g slices were taken into the anhydrous ethanol solution. The absorbance of LNG in the solution was measured in the solution after 24 h. The results showed that the silicone model was completely transparent and homogeneous. After placing the hyaline model of the uterine hyaline model 30,60 D, the 22 comparison of the concentration of LNG in each group was statistically significant (P0.01) the decrease of the concentration of.LNG in the silica gel imitated uterus was decreasing with the increase of the internal wall distance of the body cavity. Conforming to the linear law. Conclusion the establishment of the silicone imitated model of the silica gel and the concentration gradient of LNG in the wall of the body provide a theoretical basis for the treatment of some gynecologic diseases by LNG intrauterine placement.

【作者單位】： 遵義醫(yī)學院附屬婦女兒童醫(yī)院婦科;
【基金】：國家自然科學基金資助項目(NO:81660293)
【分類號】：R711.71

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