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病理類型、年齡與宮頸癌術(shù)后復(fù)發(fā)相關(guān)性的Meta分析

發(fā)布時(shí)間:2018-04-22 09:00

  本文選題:宮頸癌 + 術(shù)后復(fù)發(fā) ; 參考:《現(xiàn)代婦產(chǎn)科進(jìn)展》2015年12期


【摘要】:目的:綜合評價(jià)宮頸癌術(shù)后復(fù)發(fā)與病理類型及年齡的關(guān)系。方法:計(jì)算機(jī)檢索2009年4月至2015年4月Pub Med數(shù)據(jù)庫、Elsevier數(shù)據(jù)庫、Springer Link數(shù)據(jù)庫、LWW數(shù)據(jù)庫、CNKI數(shù)據(jù)庫、Cochrane圖書館、Embase數(shù)據(jù)庫、中國生物醫(yī)學(xué)文獻(xiàn)數(shù)據(jù)庫、數(shù)字化期刊全文數(shù)據(jù)庫(萬方)等國內(nèi)外數(shù)據(jù)庫,納入研究宮頸癌術(shù)后復(fù)發(fā)危險(xiǎn)因素的文獻(xiàn),對資料進(jìn)行質(zhì)量評價(jià)和數(shù)據(jù)提取后,采用Cochrane協(xié)作網(wǎng)提供的Revman 5.3軟件對各研究數(shù)據(jù)進(jìn)行合并和分析。結(jié)果:檢索到符合納入標(biāo)準(zhǔn)的文獻(xiàn)7篇,復(fù)發(fā)病例466例,未復(fù)發(fā)病例2473例。Meta分析結(jié)果顯示,非鱗癌(腺癌和腺鱗癌)和鱗癌的復(fù)發(fā)率相比較,差異有統(tǒng)計(jì)學(xué)意義[OR=2.88,95%CI(1.75,4.76),P=0.01];腺癌和腺鱗癌的復(fù)發(fā)率比較,差異有統(tǒng)計(jì)學(xué)意義[OR=1.74,95%CI(0.93,3.25),P=0.08];年齡(47±1)歲和年齡≥(47±1)歲的復(fù)發(fā)率比較,差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:不同病理類型的宮頸癌術(shù)后復(fù)發(fā)率非鱗癌大于鱗癌;年齡與宮頸癌患者的術(shù)后復(fù)發(fā)無關(guān)。
[Abstract]:Objective : To evaluate the relationship between recurrence and pathological type and age of cervical carcinoma . Methods : From April 2009 to April 2015 , the database , Elsevier database , Springer Link database , LWW database , CNKI database , database , Embase database , Chinese biomedical literature database and digital periodical full - text database ( Wanfang ) were combined and analyzed . The results showed that the recurrence rate of non - squamous cell carcinoma ( adenocarcinoma and adenosquamous cell carcinoma ) was significantly higher than that of squamous cell carcinoma ( P = 0 . 08 ) ; age ( 47 鹵 1 ) years and age 鈮,

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