本文選題：陰道微生態(tài) + 菌群失調��； 參考：《山東醫(yī)藥》2017年20期

【摘要】：目的探討外陰疾病患者陰道微生態(tài)狀況及其影響因素。方法選取以外陰不適(外陰瘙癢,陰道分泌物增多、有異味)就診的患者5 538例,年齡18~78歲。均取陰道分泌物,檢測陰道微生態(tài)狀況及陰道乳酸桿菌檢出率,分析年齡、避孕方式與外陰疾病者陰道微生態(tài)狀況及乳酸桿菌檢出情況的關系。結果陰道微生態(tài)正常1 568例(28.3%);異常2 447例(44.2%),其中細菌性陰道病855例(15.4%)、外陰假絲酵母菌病638例(11.5%)、滴蟲陰道炎63例(1.1%)、需氧菌性陰道炎120例(2.1%)、細胞溶解性陰道病8例(0.1%)、混合感染282例(5.1%)、菌群抑制481例(8.7%);陰道微生態(tài)失調(微生態(tài)狀況異常,但未明確感染)1 523例(27.5%)。50~78歲年齡段者陰道乳酸桿菌檢出率(42.9%)低于其他年齡段者(P均0.05)。采用避孕套避孕的外陰疾病患者陰道乳酸桿菌檢出率(75.2%)高于口服避孕藥(53.1%)和宮內節(jié)育器(61.6%)避孕者(P均0.05)。細菌性陰道病、外陰假絲酵母菌病、滴蟲陰道炎患者陰道乳酸桿菌檢出率均低于陰道微生態(tài)正常人群(P均0.05),細菌性陰道病患者檢出率明顯低于外陰假絲酵母菌病患者(P0.05)。結論外陰不適患者多數(shù)存在陰道微生態(tài)平衡失調,易引發(fā)細菌性陰道病、外陰假絲酵母菌病等陰道炎癥;年齡50歲、采用口服避孕藥和宮內節(jié)育器避孕及細菌性陰道病、假絲酵母菌病等陰道炎癥者陰道乳酸桿菌數(shù)量少,是陰道微生態(tài)失調的主要影響因素。
[Abstract]:Objective to investigate the vaginal microecology of vulvar disease patients and its influencing factors. Methods 5538 patients with vulvar discomfort (vulva pruritus, vaginal discharge increased, smell) were selected, aged 1878 years. The vaginal microecological status and the detection rate of Lactobacillus vaginalis were detected. The relationship between age, contraceptive methods and vaginal microecological status and detection of Lactobacillus in vulva disease patients was analyzed. Results there were 1 568 cases of normal vaginal microecology, 2 447 cases of abnormal vaginitis, including 855 cases of bacterial vaginosis, 638 cases of vulvar candidiasis, 63 cases of trichomonas vaginitis, 120 cases of aerobic vaginitis, 8 cases of cytolytic vaginosis, and 0.1% of them, respectively, among them, 1 568 cases were normal, 2 447 cases were abnormal, 8 cases were bacterial vaginosis, 638 cases were Candida vulva mycelia, 63 cases were trichomonal vaginitis, 120 cases were aerobic vaginitis, and 8 cases were cytolytic vaginosis. 282 cases of mixed infection, 481 cases of bacteriological inhibition, and 8.7% of vaginal microecology. However, the detection rate of Lactobacillus vaginalis in 1 523 cases of undefined infection was lower than that of other age groups (P < 0.05). The detection rate of Lactobacillus vaginalis in the age group of 78 years old was lower than that in the other age groups (P < 0.05). The detection rate of Lactobacillus vaginalis in vulvar disease patients using condom was higher than that of oral contraceptive pill (53.1%) and intrauterine contraceptive device (61.6%). The detection rate of Lactobacillus vaginalis in patients with bacterial vaginosis, vulvar candidiasis and trichomonas vaginitis was lower than that in normal vaginal microecological population (P 0.05), and the detection rate of bacterial vaginosis was significantly lower than that in vulvar Candida cerevitis patients (P 0.05). Conclusion most of the patients with vulvar discomfort have vaginal microecological imbalance, which may lead to vaginal inflammation, such as bacterial vaginosis, vulvar candidiasis, etc. The patients are 50 years old and use oral contraceptives and intrauterine devices for contraception and bacterial vaginosis. The number of lactobacillus vaginalis in patients with vaginal inflammation such as Candida cerevitis is low, which is the main influencing factor of vaginal microecological disorder.
【作者單位】： 云南省第一人民醫(yī)院;
【分類號】：R711.3

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