發(fā)布時間：2018-04-12 21:47

  本文選題：養(yǎng)血復(fù)宮丸 + 血瘀型　； 參考：《山東中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:觀察養(yǎng)血復(fù)宮丸對血瘀型剖宮產(chǎn)產(chǎn)后惡露不絕患者的臨床療效,為養(yǎng)血復(fù)宮丸的臨床應(yīng)用提供科學(xué)依據(jù)。方法:收集自2015年1月~2016年1月期間濟寧市中醫(yī)院門診和住院的符合臨床診斷標準的行剖宮產(chǎn)手術(shù)產(chǎn)婦產(chǎn)后惡露不絕患者92例,依據(jù)隨機數(shù)字表法隨機分為治療組46例與對照組46例。對照組采用新生化顆粒溫水沖服,一次2袋×6g,每日3次;治療組使用濟寧市中醫(yī)院院內(nèi)制劑養(yǎng)血復(fù)宮丸進行治療,口服,一次9g,每日3次。兩組療程均以7d為1療程,連續(xù)給藥2個療程。比較兩組治療后疾病療效、中醫(yī)證候療效,治療前后證候積分、不同年齡段治療前后中醫(yī)證候積分、不同治療階段中醫(yī)證候積分、各分項證候積分、子宮體積變化、血紅蛋白、紅細胞、血漿黏度、血沉、纖維蛋白原變化及用藥期間不良反應(yīng)發(fā)生情況。結(jié)果:(1)治療組疾病總有效率(95.65%)高于對照組(78.26%),且具有統(tǒng)計學(xué)差異(P0.05);(2)治療組證候總有效率(93.48%)高于對照組(76.09%),且具有統(tǒng)計學(xué)差異(P0.05);(3)兩組證候積分治療后明顯下降,且具有統(tǒng)計學(xué)差異(P0.05);治療組證候積分治療后明顯低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);(4)兩組不同年齡段證候積分治療后明顯降低,且具有統(tǒng)計學(xué)差異(P0.05);治療組不同年齡段證候積分治療后明顯低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);而兩組不同年齡段證候積分治療后組內(nèi)比較無統(tǒng)計學(xué)差異(P0.05);(5)兩組治療2個療程證候積分較治療1個療程明顯降低,且具有統(tǒng)計學(xué)差異(P0.05);治療組治療1個療程和治療2個療程證候積分均明顯低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);(6)兩組持續(xù)時間、血量、血色、血質(zhì)、小腹疼痛積分治療后明顯下降,且具有統(tǒng)計學(xué)差異(P0.05);治療組持續(xù)時間、血量、血色、血質(zhì)、小腹疼痛積分治療后低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);(7)兩組子宮體積治療后明顯降低,且具有統(tǒng)計學(xué)差異(P0.05);治療組子宮體積治療后明顯低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);(8)兩組血漿黏度、血沉、纖維蛋白原治療后較治療前下降,且具有統(tǒng)計學(xué)差異(P0.05);治療組血漿黏度、血沉、纖維蛋白原治療后低于對照組,且具有統(tǒng)計學(xué)差異(P0.05);(9)兩組均未見嚴重用藥不良反應(yīng)。結(jié)論:養(yǎng)血復(fù)宮丸治療血瘀型剖宮產(chǎn)產(chǎn)后惡露不絕患者療效顯著,可明顯改善患者證候,可明顯降低患者子宮體積,且可降低血漿黏度、血沉、纖維蛋白原,安全可靠,具有重要研究價值,值得臨床進一步推廣應(yīng)用。
[Abstract]:Objective: to observe the clinical effect of Yangxue Fugong Pill on postpartum lochia caused by blood stasis type cesarean section, and to provide scientific basis for clinical application of Yangxue Fugong Pill.Methods: from January 2015 to January 2016, 92 patients with postpartum lochia in accordance with clinical diagnosis criteria were collected.According to the method of random digital table, 46 cases in treatment group and 46 cases in control group were randomly divided into treatment group and control group.The control group was treated with warm water, 2 bags 脳 6 g, 3 times a day, and the treatment group was treated with Yangxue Fugong pill, which was used in hospital of Jining City traditional Chinese Medicine Hospital, orally, 9 g once a day, 3 times a day.The course of treatment in both groups was 7 days as a course of treatment and 2 consecutive courses of administration.Compare the curative effect of the two groups after treatment, the curative effect of TCM syndrome, the integral of syndrome before and after treatment, the integral of TCM syndrome before and after treatment at different ages, the integral of TCM syndrome in different treatment stage, the integral of syndrome of each item, the change of uterine volume, the hemoglobin,Red blood cells, plasma viscosity, erythrocyte sedimentation rate, fibrinogen changes and adverse reactions during medication.Results the total effective rate of disease in the treatment group (95.65) was higher than that in the control group (78.26), and the difference was statistically significant (P 0.05). The total effective rate of syndromes in the treatment group was 93.48) higher than that in the control group (76.09%), and the difference was statistically significant (P 0.05).After treatment, the syndromes integral in the treatment group was significantly lower than that in the control group, and there was a statistical difference between the two groups.And there was statistical difference (P 0.05), the syndrome integral of different ages in the treatment group was significantly lower than that in the control group.There was no statistical difference between the two groups after the treatment of syndromes of different age groups (P0.05) the scores of two courses of treatment were significantly lower than that of one course of treatment, and there was no statistical difference between the two groups after treatment.The results showed that the duration, blood volume, blood color, blood quality and abdominal pain score in the treatment group were lower than those in the control group, and the uterine volume in the treatment group was significantly lower than that in the control group (P 0.05), and the uterine volume in the treatment group was significantly lower than that in the control group (P < 0.05).The uterine volume in the treatment group was significantly lower than that in the control group (P 0.05), and the plasma viscosity, erythrocyte sedimentation rate (ESR) and fibrinogen (Fibrinogen) in the two groups were decreased after treatment.The plasma viscosity, erythrocyte sedimentation rate and fibrinogen in the treatment group were lower than those in the control group, and there was no serious adverse drug reaction between the two groups.Conclusion: Yangxue Fugong pills has a significant effect on the treatment of postpartum lochia caused by blood stasis type cesarean section. It can obviously improve the syndromes of the patients, reduce the volume of uterus, and reduce the plasma viscosity, erythrocyte sedimentation rate, fibrinogen, and is safe and reliable.It has important research value and is worthy of further clinical application.
【學(xué)位授予單位】：山東中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R719.8

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本文編號：1741562