本文選題：單純性外陰陰道假絲酵母菌病　切入點：紅核婦潔洗液　出處：《現(xiàn)代婦產(chǎn)科進展》2017年06期 　論文類型：期刊論文

【摘要】：目的:評價紅核婦潔洗液治療單純性外陰陰道假絲酵母菌病(VVC)的有效性和安全性。方法:2014年6月至2016年6月在復旦大學附屬婦產(chǎn)科醫(yī)院門診募集單純性VVC患者,隨機分為研究組(紅核婦潔洗液組)和對照組(硝酸咪康唑軟膠囊組),分別在治療前和治療結束后1~2周、4周、8周進行真菌檢測、瘙癢評價、VVC評分、BV五項檢測及安全性評估。結果:治療后1~2周,研究組和對照組的瘙癢陽性率、真菌陽性率、VVC評分均呈顯著下降趨勢,兩組比較無顯著差異。兩組治療后4周與基線相比,p H值、唾液酸苷酶、白細胞脂酶、脯氨酸氨基肽酶陽性率顯著下降,但兩組無顯著差異。治療后8周,研究組的白細胞脂酶陽性率、VVC評分顯著低于對照組。兩組患者在治療前后血常規(guī)、生化指標、心電圖等無顯著差異,無明顯不良反應。結論:紅核婦潔洗液治療單純性VVC有效、安全,在臨床上值得進一步應用。
[Abstract]:Objective: to evaluate the efficacy and safety of Hongxufujie lotion in the treatment of simple vulvovaginal candidiasis. Methods: from June 2014 to June 2016, simple VVC patients were recruited from outpatient clinic of Department of Gynecology and Obstetrics Hospital of Fudan University. They were randomly divided into study group (Hongxufujie lotion group) and control group (miconazole nitrate soft capsule group). Results: the positive rate of pruritus and the positive rate of fungi in the study group and the control group were significantly decreased 2 weeks after treatment. The positive rates of sialidase, leucocyte lipase, proline aminopeptidase in the two groups decreased significantly 4 weeks after treatment, but there was no significant difference between the two groups at the 4th week after treatment, compared with the baseline, the positive rates of sialidase, leucocyte lipase and proline aminopeptidase were not significantly different between the two groups. The positive rate of leukocyte lipase in the study group was significantly lower than that in the control group. There was no significant difference in blood routine examination, biochemical index, electrocardiogram between the two groups before and after treatment, and no significant adverse reactions. Conclusion: Hongxufujie lotion is effective in the treatment of simple VVC. It is safe and worthy of further application in clinic.
【作者單位】： 復旦大學附屬婦產(chǎn)科醫(yī)院宮頸疾病診療中心上海市生殖內(nèi)分泌重點實驗室;復旦大學附屬婦產(chǎn)科醫(yī)院婦科;
【分類號】：R711.31

【相似文獻】

相關期刊論文 前10條

1 劉琴;焦眉懷;劉芳;;特比奈芬聯(lián)合紅核婦潔洗液治療復發(fā)性念珠菌性外陰陰道炎臨床療效規(guī)察[J];吉林醫(yī)學;2012年23期

2 趙晶;;紅核婦潔洗液治療妊娠期外陰陰道假絲酵母菌病的療效觀察[J];甘肅醫(yī)藥;2012年06期

3 聶華;;紅核婦潔洗液對某區(qū)婦女陰道炎的療效觀察[J];中國醫(yī)藥指南;2014年05期

4 高成英;劉早寧;焦靜;;紅核婦潔洗液陰道沖洗對外陰陰道_λ拷湍婦〉鬧瘟譜饔肹J];延安大學學報(醫(yī)學科學版);2012年01期

5 豆格吉;;紅核婦潔洗液治療陰道炎200例臨床觀察[J];遼寧中醫(yī)雜志;2012年04期

6 李涓;王詠梅;柏青;周彥;;紅核婦潔洗液治療早孕患者非特異性外陰陰道炎90例臨床分析[J];中外醫(yī)學研究;2011年26期

7 馬春秀;;紅核婦潔洗液配伍乳酸菌陰道膠囊治療復發(fā)性外陰陰道假絲酵母菌病210例分析[J];中國醫(yī)藥指南;2013年31期

8 王金紅;;兩種陰道沖洗液的療效比較[J];中國藥物經(jīng)濟學;2013年05期

9 祖力皮亞依明;;紅核婦潔洗液聯(lián)合伊曲康唑治療霉菌性陰道炎98例[J];中國實用醫(yī)藥;2013年26期

10 李秀蘭;楊銘越;齊曉玲;;紅核婦潔洗液預防陰式手術切口感染的臨床觀察[J];現(xiàn)代中西醫(yī)結合雜志;2010年32期

，

本文編號：1651944