發(fā)布時(shí)間：2018-03-18 14:12

  本文選題：上皮性卵巢癌　切入點(diǎn)：輔助生殖技術(shù)　出處：《浙江大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探索輔助生殖技術(shù)過程中發(fā)現(xiàn)上皮性卵巢癌的臨床特點(diǎn)和診治經(jīng)驗(yàn)。方法：回顧我院2012年1月～2016年2月在輔助生殖技術(shù)過程中發(fā)現(xiàn)的上皮性卵巢癌2例,并通過文獻(xiàn)檢索收集9例個(gè)案,提取相關(guān)信息。結(jié)果：在初次接受ART治療后半年內(nèi)發(fā)現(xiàn)卵巢癌者3例,考慮與輔助生殖技術(shù)不相關(guān)；接受ART次數(shù)小于等于4次者4例,卵巢癌病理類型均為漿液性腺癌,平均發(fā)病年齡27.8±3.1歲。接受ART治療次數(shù)大于等于5次者4例,病理類型均為子宮內(nèi)膜樣腺癌,平均發(fā)病年齡39±1.2歲,其中1例不孕類型為排卵障礙,3例為男方不孕。選擇保留生育功能者共4例,1例為IC1期、G1分化子宮內(nèi)膜樣腺癌,行雙側(cè)附件切除而保留子宮；1例為IA期、G1分化漿液性腺癌,行單側(cè)附件切除術(shù)、保留子宮；1例為IC期、子宮內(nèi)膜樣腺癌,1例為孕中期發(fā)現(xiàn)的漿液性腺癌行單側(cè)附件切除術(shù)。根據(jù)已有數(shù)據(jù),隨訪時(shí)間6個(gè)月～6年,均為無瘤生存,未隨訪到死亡或復(fù)發(fā)病例。結(jié)論：輔助生殖技術(shù)前應(yīng)全面檢查排除卵巢癌,反復(fù)多次的ART治療可能會(huì)增加卵巢子宮內(nèi)膜樣腺癌的發(fā)生風(fēng)險(xiǎn),在輔助生殖技術(shù)發(fā)現(xiàn)的卵巢癌行保留生育功能手術(shù)應(yīng)慎重。
[Abstract]:Objective: to explore the clinical features, diagnosis and treatment of epithelial ovarian cancer in the course of assisted reproductive technique. Methods: two cases of epithelial ovarian cancer from January 2012 to February 2016 in our hospital were reviewed. The results showed that ovarian cancer was found in 3 cases within six months after initial ART treatment, which was not related to assisted reproductive technology, and 4 cases received ART less than 4 times. The pathological types of ovarian cancer were serous adenocarcinoma with an average onset age of 27.8 鹵3.1 years. 4 cases were treated with ART for more than 5 times. The pathological types were endometrioid adenocarcinoma with an average onset age of 39 鹵1.2 years. One case of infertility was ovulation disorder 3 cases were male infertility, 4 cases were selected to retain fertility function, 1 case was endometrial adenocarcinoma differentiated from IC1 stage G 1, and 1 case was treated with bilateral appendage resection and 1 case with IA stage G 1 differentiated serous adenocarcinoma. Unilateral appendectomy was performed in 1 case of IC stage and 1 case of endometrial adenocarcinoma was found in the second trimester of pregnancy. According to the available data, the follow-up time was 6 months to 6 years, and all of them were tumor-free. Conclusion: ovarian cancer should be ruled out before assisted reproductive technique. Repeated ART treatment may increase the risk of endometrioid adenocarcinoma of ovary. Surgery for preserving reproductive function in ovarian cancer found by assisted reproductive technology should be cautious.
【學(xué)位授予單位】：浙江大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R737.31;R714.8

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 陽(yáng)志軍;李力;;促排卵治療后發(fā)現(xiàn)卵巢上皮性癌二例[J];中華婦產(chǎn)科雜志;2013年01期

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本文編號(hào)：1629923