本文選題：外泌體　切入點(diǎn)：卵巢癌　出處：《東南大學(xué)學(xué)報(bào)(醫(yī)學(xué)版)》2017年02期 　論文類(lèi)型：期刊論文

【摘要】：卵巢癌是死亡率居首位的女性生殖系統(tǒng)惡性腫瘤。外泌體是由細(xì)胞內(nèi)多囊泡與細(xì)胞膜融后釋放到細(xì)胞外環(huán)境中的一種直徑在30~100 nm的小囊泡。越來(lái)越多的研究發(fā)現(xiàn)外泌體是細(xì)胞間通訊的關(guān)鍵因子,在腫瘤細(xì)胞及腫瘤微環(huán)境的物質(zhì)和信號(hào)交流中發(fā)揮重要作用。外泌體在卵巢癌的發(fā)生發(fā)展中亦有重要的調(diào)控作用,可能成為卵巢癌診斷和治療的新靶點(diǎn)。
[Abstract]:Ovarian cancer is the highest mortality malignant tumor of female reproductive system. Exocrine body is a small vesicle which is released into the extracellular environment by the fusion of cell multiple vesicles and cell membrane. More and more studies have found that ovarian cancer is about 30 ~ 100 nm in diameter. Exocrine body is a key factor in intercellular communication. It plays an important role in the communication of substances and signals in tumor cells and tumor microenvironment. Exocrine may also play an important role in the development of ovarian cancer and may become a new target for the diagnosis and treatment of ovarian cancer.
【作者單位】： 南京醫(yī)科大學(xué)附屬南京醫(yī)院婦科;南京醫(yī)科大學(xué)附屬南京醫(yī)院中心實(shí)驗(yàn)室;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81572557) 南京市醫(yī)學(xué)科技發(fā)展專(zhuān)項(xiàng)資金資助項(xiàng)目(ZKX15029)
【分類(lèi)號(hào)】：R737.31
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本文編號(hào)：1577874