輸卵管間質(zhì)部妊娠術(shù)后子宮破裂4例病例報(bào)告及文獻(xiàn)復(fù)習(xí)
本文關(guān)鍵詞: 子宮破裂 輸卵管間質(zhì)部妊娠 危險(xiǎn)因素 臨床特點(diǎn) 出處:《浙江大學(xué)》2017年碩士論文 論文類型:學(xué)位論文
【摘要】:目的:輸卵管間質(zhì)部妊娠是異位妊娠的一種特殊類型,目前手術(shù)多采用腹腔鏡下患側(cè)輸卵管及部分宮角切除。同時(shí)越來越多的術(shù)后患者存在生育要求,而間質(zhì)部妊娠術(shù)后患者再次妊娠期間存在子宮破裂風(fēng)險(xiǎn)。因而本文旨在總結(jié)輸卵管間質(zhì)部妊娠術(shù)后再次妊娠期間子宮破裂的患者的臨床特征,從而能夠?yàn)榕R床診治提供參考。方法:回顧性分析我院1999-2016年收治的4例輸卵管間質(zhì)部妊娠術(shù)后再次妊娠期間子宮破裂患者的臨床資料,結(jié)合復(fù)習(xí)相關(guān)文獻(xiàn),探討輸卵管間質(zhì)部妊娠術(shù)后子宮破裂的危險(xiǎn)因素、臨床特點(diǎn)、處理及預(yù)后。結(jié)果:1999年11月至2016年10月我院共有283例子宮破裂患者,其中輸卵管間質(zhì)部妊娠術(shù)后子宮破裂4例。本文報(bào)道的4例患者均為育齡期女性,年齡為28-42歲,既往均有不良孕史,所有患者均曾因輸卵管異位妊娠行單側(cè)或雙側(cè)輸卵管切除史。而4例患者末次妊娠均為輸卵管間質(zhì)部妊娠,并均行腹腔鏡下患側(cè)宮角切除術(shù),僅2例官角切除后進(jìn)行縫合。而此次間質(zhì)部妊娠術(shù)后再次妊娠僅有一例為自然妊娠,其余均為輔助生育妊娠。手術(shù)至再次妊娠時(shí)間間隔,最短為0.52年,最長為2.25年。4例患者分娩孕周最小17周,最大37+1周,其中2例為雙胎妊娠,2例患者存在胎位異常,而4例患者妊娠子宮破裂均在既往宮角瘢痕處。同時(shí)4例妊娠子宮破裂患者中2例均無明顯不適主訴,1例由B超提示,1例由術(shù)中探查發(fā)現(xiàn);1例患者僅有輕微腹痛主訴,一例患者主訴為持續(xù)劇烈腹痛伴惡心腹瀉,于首診時(shí)被誤診為消化道疾病。最終4例患者均僅采取子宮修補(bǔ)術(shù),其中2例胎兒死亡。術(shù)后均順利出院,恢復(fù)可,無月經(jīng)改變,僅有1例患者有再生育要求。結(jié)論:輸卵管間質(zhì)部術(shù)后再次妊娠期間存在子宮破裂的風(fēng)險(xiǎn),在臨床上雖然并不多見,但一旦發(fā)生,其臨床癥狀并不明顯,易誤診漏診,對(duì)母嬰威脅較大。因而對(duì)輸卵管間質(zhì)部妊娠的患者,需選擇合適的治療方式,并注意術(shù)中的操作和術(shù)后的避孕時(shí)間,再次妊娠期間需加強(qiáng)監(jiān)測(cè),警惕子宮破裂風(fēng)險(xiǎn),必要時(shí)行剖官產(chǎn)術(shù)終止妊娠。
[Abstract]:Objective: interstitial tubal pregnancy is a special type of ectopic pregnancy. However, there is a risk of uterine rupture during secondary pregnancy in patients with interstitial pregnancy. Therefore, this article aims to summarize the clinical features of patients with uterine rupture during secondary pregnancy after tubal interstitial pregnancy. Methods: the clinical data of 4 cases of uterine rupture during secondary pregnancy after tubal interstitial pregnancy in our hospital from 1999 to 2016 were analyzed retrospectively. To investigate the risk factors, clinical features, management and prognosis of uterine rupture after tubal interstitial pregnancy. Results: from November 1999 to October 2016, there were 283 cases of uterine rupture in our hospital. There were 4 cases of uterine rupture after tubal interstitial pregnancy. All the patients had undergone unilateral or bilateral salpingotomy because of ectopic tubal pregnancy. Only 2 cases were sutured after keratectomy. However, only one case of secondary pregnancy after interstitial pregnancy was natural pregnancy, and the rest were assisted pregnancy. The interval between operation and re-pregnancy was 0.52 years, the shortest time interval between operation and re-pregnancy was 0.52 years, and the time interval between operation and re-pregnancy was 0.52 years. The longest pregnancy was 2.25 years. The gestational age was 17 weeks and the maximum was 37.1 weeks. Among them, 2 cases were twin pregnancy and 2 cases had abnormal fetal position. However, 4 cases of pregnancy uterine rupture were located in the scar of the previous uterine horn, and 2 of the 4 cases of pregnancy with uterine rupture had no obvious complaints of discomfort, 1 case was revealed by B-ultrasound, 1 case was found to have mild abdominal pain by intraoperative exploration, and 1 case was found to have only mild abdominal pain. One patient complained of persistent severe abdominal pain with nausea and diarrhea, which was misdiagnosed as digestive tract disease at the first visit. In the end, all the 4 patients were treated with uterine repair only, 2 of them died of fetal death. Conclusion: there is a risk of uterine rupture during the second pregnancy after tubal tubal interstitial surgery. Although it is rare in clinic, its clinical symptoms are not obvious, and it is easy to be misdiagnosed and missed. Therefore, the patients with tubal interstitial pregnancy should choose the appropriate treatment method, pay attention to the operation during operation and the time of contraception after operation, strengthen the monitoring during the second pregnancy, and be on guard against the risk of uterine rupture. Termination of pregnancy by dissection if necessary.
【學(xué)位授予單位】:浙江大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R713.8
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