本文關鍵詞： 抗苗勒管激素 高齡婦女 卵巢功能 女性激素　出處：《中國婦幼保健》2016年19期 　論文類型：期刊論文

【摘要】：目的探討抗苗勒管激素(Anti-mullerian hormone,AMH)在高齡婦女卵巢功能評估中的價值。方法收集2014年10月-2015年2月在柳州市婦幼保健院門診接受咨詢的高齡婦女100例,根據(jù)其月經狀態(tài)將其分正常組32例,圍絕經期組35例,卵巢早衰(Premature Ovarian Failure,POF)組33例,比較各組的黃體生成素(Luteinizing Hormone,LH)、卵泡刺激素(Follicle-Stimulating Hormone,FSH)、雌二醇(Estradiol,E2)和AMH水平,分析圍絕經期組女性入組時、6個月、12個月時LH、FSH、E2和AMH水平變化,對比隨訪自然妊娠女性與非妊娠女性在入組時的LH、FSH、E2和AMH水平差異。結果圍絕經期組血清FSH水平明顯高于正常組(P0.05),AMH水平明顯低于正常組(P0.05);POF組LH、FSH水平明顯高于正常組和圍絕經期組(P0.05),E2、AMH水平明顯低于正常組和圍絕經期組(P0.05)。圍絕經期組入組后6個月、12個月時AMH水平較初測時均明顯降低(P0.05),12個月時AMH水平較6個月時明顯降低(P0.05);12個月時LH、FSH水平較初測、6個月時均明顯升高(P0.05),E2水平較初測、6個月時均明顯降低(P0.05)。正常組中妊娠婦女入組的初測AMH水平明顯高于非妊娠婦女的初測水平(P0.05)。結論 AMH能較早、準確地反映高齡女性的卵巢功能變化,評估其自然受孕能力,因此在高齡婦女的生育能力評估中具有高的臨床應用價值。
[Abstract]:Objective to investigate the value of anti-mullerian hormone AMH in the evaluation of ovarian function in elderly women. Methods 100 elderly women who received consultation in the outpatient clinic of Liuzhou Maternal and Child Health Hospital from October 2014 to February 2015 were collected. According to the menstrual state, 32 cases were divided into normal group, 35 cases in peri-menopausal period and 33 cases in premature Ovarian failure (POF) group. The levels of luteinizing Hormoneinizing LHH, Follicle-Stimulating HormoneFSHSH2, Estradiol E2 and Estradiolol E2 were compared. To analyze the changes of FSHE2 and AMH levels in peri-menopausal women at 6 months and 12 months, respectively. Results the serum FSH level in the perimenopausal group was significantly higher than that in the normal group (P 0.05) and that in the control group was significantly higher than that in the normal group. The level of P0.05E2AH in the peri-menopausal group was significantly lower than that in the normal group and the peri-menopausal group. The AMH level in the peri-menopausal group was significantly lower than that in the first measured group at 12 months, the AMH level at 12 months was significantly lower than that at 6 months, and at 12 months after menopause, it was significantly lower than that at 6 months after entering the group, and at 12 months after menopause, the AMH level was significantly lower than that at 6 months. The level of AMH in normal pregnant women was significantly higher than that in non-pregnant women (P 0.05). Conclusion the level of AMH was earlier in normal pregnant women than that in non-pregnant women, and the level of P0. 05% E 2 was significantly higher than that in normal women at 6 months, and the level of P0. 05% E 2 was significantly lower in normal pregnant women than that in non pregnant women at 6 months, and the level of P0. 05 in normal women was significantly higher than that in non pregnant women. It can accurately reflect the changes of the ovarian function of the elderly women and evaluate their natural ability to conceive, so it has high clinical application value in the evaluation of the fertility of the elderly women.
【作者單位】： 柳州市婦幼保健院檢驗科;
【基金】：廣西壯族自治區(qū)衛(wèi)計委醫(yī)學科研基金(Z2014374)
【分類號】：R711

【相似文獻】

相關期刊論文 前10條

1 何玉冰;;高齡婦女的妊娠與分娩分析[J];中國現(xiàn)代藥物應用;2010年24期

2 王瓊;;高齡婦女與生殖助孕[J];中國實用婦科與產科雜志;2006年10期

3 耿曉星,馬榮,高慶玉;高齡婦女宮頸疾病與人乳頭瘤病毒感染相關性[J];中國腫瘤;2005年09期

4 劉麗慧,陳豪;高齡婦女接受卵子捐獻后的妊娠結果[J];國外醫(yī)學(計劃生育分冊);1996年02期

5 焦?jié)尚?莊廣倫,周燦權,徐艷文,梁曉燕,李俐琳,鄧明芬;高齡婦女接受體外受精-胚胎移植的結局[J];中華婦產科雜志;2002年04期

6 孫顯斌;;高齡婦女的內分泌——伴隨衰老的內分泌變化[J];國外醫(yī)學.婦產科學分冊;1991年02期

7 宋湘;;專家呼吁:回歸自然受孕[J];婚育與健康;2009年21期

8 王玉香;高齡婦女節(jié)育環(huán)嵌頓1例[J];黔南民族醫(yī)專學報;1998年03期

9 ;女性年輕時多次流產導致后期懷孕難[J];科學大觀園;2007年11期

10 田小紅;;高齡婦女盆腔包塊延誤診治的分析[J];中外醫(yī)療;2011年22期

相關重要報紙文章 前2條

1 羅軒紅 本報記者 劉旭;高齡婦女再孕要提前做好相關檢查和評估[N];中國婦女報;2014年

2 馮武勇;卵子冷凍新技術,助高齡婦女當媽[N];新華每日電訊;2006年

，

本文編號：1520633