本文關(guān)鍵詞： 剖宮產(chǎn)術(shù) 子宮瘢痕妊娠 子宮動脈栓塞 Meta分析　出處：《婦產(chǎn)與遺傳(電子版)》2016年04期 　論文類型：期刊論文

【摘要】：目的系統(tǒng)評價子宮動脈栓塞在剖宮產(chǎn)術(shù)后子宮瘢痕妊娠中的療效。方法以動脈栓塞(arterial embolization)、子宮瘢痕妊娠(cesarean scar pregnancy,CSP)、隨機對照實驗(randomized controlled trial,RCT)、剖宮產(chǎn)(cesarean section)、甲氨蝶呤(methotrexate,MTX)等檢索詞全面檢索Cochrane圖書館、Embase、Pub Med,并檢索中國生物醫(yī)學文獻數(shù)據(jù)庫(CBM)、相關(guān)期刊論文(VIP)、中文科技期刊數(shù)據(jù)庫(CNKI)和萬方數(shù)據(jù)庫(Wanfang Data),檢索時間截止至2015年5月,并將符合納入標準的文獻按照Cochrane協(xié)作網(wǎng)推薦的方法進行系統(tǒng)評價。結(jié)果共納入的6篇文獻,4篇比較子宮動脈栓塞術(shù)與MTX療效;2篇比較子宮動脈化療栓塞術(shù)與MTX療效,其中1篇比較不同栓塞劑(明膠海綿及聚乙烯醇顆粒)化療栓塞和單純MTX的療效。系統(tǒng)評價結(jié)果顯示子宮動脈(化療)栓塞組住院時間(MD-28.29 d,95%CI:-31.08~-25.51,P0.00001)、出血量(MD-448.47 m L,95%CI:-513.57~-383.37,P0.00001)、血β-HCG恢復(fù)正常時間(MD-20.167 d,95%CI:-33.01~-7.32,P=0.002)及治療成功率(RR:1.35,95%CI:1.05~1.73,P=0.02)均優(yōu)于甲氨蝶呤組,兩組月經(jīng)恢復(fù)時間(MD-2.93 d,95%CI:-6.03~0.16,P=0.06)、副反應(yīng)發(fā)生率(RR:0.96,95%CI:0.51~1.82,P=0.90)無統(tǒng)計學意義。結(jié)論子宮動脈栓塞術(shù)治療剖宮產(chǎn)術(shù)后瘢痕妊娠療效確切。
[Abstract]:Objective to evaluate the efficacy of uterine artery embolization in uterine scar pregnancy after cesarean section. Methods artery embolization with arterial embolization of uterine scar pregnancy, uterine scar pregnancy Cesarean scar pregnancyn controlled, randomized controlled trialator RCTT, cesarean sectionation, methotrexate methotrexate. A comprehensive search of Cochrane Library Embase Pub Medand, and the search of Chinese Biomedical Literature Database (CBM), Chinese Journal Full-text Database (Cochrane), Chinese Journal of Science and Technology Database (CNKI) and Wanfang data Base (Wanfang data) were conducted. The search time was up to May 2015. According to the method recommended by Cochrane Cooperative Network, a systematic evaluation was carried out on the literature according to the inclusion criteria. Results there were 6 articles, 4 articles, comparing uterine artery embolization with MTX and 2 articles comparing uterine arterial chemoembolization with MTX. One of them compared the effects of different embolization agents (gelfoam and polyvinyl alcohol granules) on chemoembolization and simple MTX. The results of systematic evaluation showed that the hospitalization time of uterine artery embolization group was MD-28.29 d ~ 95 and CI: -31.08- 25.51U P 0.00001, the amount of bleeding was MD-448.47mL9595CIw-513.57C7-383.3ng / P 0.00001, and the blood 尾 -HCG was recovered by 尾 -HCG. In normal time, MD-20.167 d ~ (95) CI: -33.01 ~ -7.32% P0. 002) and the success rate of treatment were higher than those of methotrexate group (R: 1.35 ~ 95 CI: 1.05 ~ 1.73 P0. 02). There was no significant difference in the recovery time of menstruation between the two groups (MD-2.93 d ~ 95 CI: -6.03) 0.16% P0.06, and the incidence of side effects (RR: 0.96 ~ 95CI: 0.51C: 1.82P 0.90). Conclusion uterine artery embolization is effective in the treatment of scar pregnancy after cesarean section.
【作者單位】： 深圳市寶安區(qū)婦幼保健院產(chǎn)科;
【分類號】：R714.22

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