本文關(guān)鍵詞： 小劑量 右美托咪定 宮頸腫瘤 外科手術(shù) 微創(chuàng)性 手術(shù)后惡心嘔吐　出處：《重慶醫(yī)學》2017年36期 　論文類型：期刊論文

【摘要】：目的探究小劑量右美托咪定對宮頸癌微創(chuàng)手術(shù)患者惡心嘔吐的影響。方法選取2014年6月至2016年6月海南省中醫(yī)院收治的122例宮頸癌微創(chuàng)手術(shù)患者為研究對象,將患者采用隨機數(shù)表法分為對照組和觀察組,各61例。麻醉誘導前觀察組患者經(jīng)1min靜脈注射0.1μg/kg右美托咪定,對照組患者給予等量生理鹽水。對比兩組患者圍術(shù)期各項指標、惡心嘔吐分級和不良反應發(fā)生情況。結(jié)果兩組患者的麻醉時間、手術(shù)時間、睜眼時間、自主呼吸恢復時間、拔除氣管導管時間比較,差異無統(tǒng)計學意義(P0.05)。觀察組患者術(shù)中心率(HR)最低值低于對照組患者,心動過緩發(fā)生率高于對照組患者,差異有統(tǒng)計學意義(P0.05)。T2時刻(術(shù)后1.0h)觀察組患者惡心嘔吐分級(PONV)Ⅱ級構(gòu)成比顯著低于對照組T2時刻PONVⅡ級構(gòu)成比,T4時刻(術(shù)后24.0h)觀察組患者惡心嘔吐發(fā)生率顯著低于對照組,差異有統(tǒng)計學意義(P0.05)。對照組患者的躁動發(fā)生率高于觀察組,差異有統(tǒng)計學意義(P0.05)。結(jié)論小劑量右美托咪定能夠顯著緩解宮頸癌微創(chuàng)手術(shù)患者術(shù)后惡心嘔吐,并能夠降低躁動發(fā)生率,且不會影響麻醉效果,但容易發(fā)生心動過緩。
[Abstract]:Objective to investigate the effect of low-dose dexmetomidine on nausea and vomiting in patients with cervical cancer undergoing minimally invasive surgery. Methods 122 patients with cervical cancer undergoing minimally invasive surgery from June 2014 to June 2016 in Hainan Provincial Hospital of traditional Chinese Medicine were selected. Who is the object of study. The patients were randomly divided into control group (n = 61) and observation group (n = 61). Before anesthesia induction, patients in observation group were given 0.1 渭 g / kg dexmetidine intravenously before anesthesia induction. The patients in the control group were given the same amount of normal saline. The perioperative indexes, nausea and vomiting grade and adverse reactions were compared between the two groups. Results the anesthesia time, operation time and eye opening time were compared between the two groups. There was no significant difference in the time of spontaneous respiratory recovery and tracheobronchial extubation (P 0.05). The lowest value of heart rate in the observation group was lower than that in the control group. The incidence of bradycardia was higher than that in control group. The difference was statistically significant (P 0.05). T2 (1.0 h after operation) the nausea and vomiting grade of the patients in the observation group was PONV1). The grade 鈪，

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