發(fā)布時間：2018-01-22 09:49

  本文關(guān)鍵詞： 血清CA 卵巢上皮癌 治療后復(fù)發(fā)　出處：《中國婦產(chǎn)科臨床雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的探討卵巢上皮癌治療前后血清CA125變化模式對判斷預(yù)后和診斷復(fù)發(fā)的價值。方法采用放射免疫方法對152例卵巢上皮性癌患者治療前后血清CA125進(jìn)行連續(xù)監(jiān)測,并采用相關(guān)的統(tǒng)計學(xué)方法分析卵巢上皮癌治療前后血清CA125變化模式對判斷預(yù)后和診斷復(fù)發(fā)的價值。結(jié)果 (1)治療前血清CA125≤35 U/ml者的PFS和OS高于治療前血清CA12535 U/ml者(P0.05);治療后血清CA125呈對數(shù)下降者或1個月之內(nèi)下降至正常者的PFS和OS高于治療后血清CA125呈非對數(shù)下降者或大于1個月下降至正常者(P0.05);(2)多因素Cox回歸模型分析顯示,治療前CA125含量(相對危險度量3.274,P=0.025)和治療后血清CA125含量下降速度(相對危險度量6.213,P=0.002)是患者預(yù)后的獨立因素;(3)血清CA125診斷卵巢上皮癌復(fù)發(fā)的ROC曲線下面積為0.879,其診斷敏感性和特異性分別為67.39%和86.79%。結(jié)論卵巢上皮癌治療前后血清CA125變化模式對對判斷卵巢上皮性癌預(yù)后和診斷復(fù)發(fā)有重要意義。
[Abstract]:Objective to investigate the value of serum CA125 pattern in predicting prognosis and diagnosing recurrence of ovarian epithelial carcinoma before and after treatment. Methods Serum CA1 in 152 patients with ovarian epithelial carcinoma before and after treatment was studied by radioimmunoassay. 25 continuous monitoring. The changes of serum CA125 in patients with ovarian epithelial carcinoma before and after treatment were analyzed by correlation statistical method. The levels of PFS and OS in patients with serum CA125 鈮，

本文編號：1454345