短期靜脈高糖營養(yǎng)聯(lián)合胰島素治療妊娠劇吐的臨床觀察
發(fā)布時間:2018-01-21 03:59
本文關鍵詞: 妊娠劇吐 靜脈高糖營養(yǎng) 胰島素 出處:《中國實用醫(yī)藥》2014年04期 論文類型:期刊論文
【摘要】:目的探討短期靜脈高糖營養(yǎng)聯(lián)合胰島素治療妊娠劇吐的臨床療效。方法將130例妊娠劇吐癥狀較重患者按其意愿分為兩組,對照組58例采用常規(guī)補液治療(每日靜脈輸注葡萄糖液及葡萄糖鹽水3000 ml,輸液中加入氯化鉀、維生素C、維生素B6等,并給予維生素B1肌內注射。)治療組72例除與對照組相同靜脈補液外,前3 d給予靜脈高糖營養(yǎng)短期治療(5%葡萄糖注射液500 ml+50%葡萄糖注射液40~60 ml+正規(guī)胰島素12 U)。結果治療3 d后,治療組及對照組的痊愈率分別為51.4%、25.9%(P0.01),總有效率分別為100%、77.6%(P0.01);治療5 d后,治療組及對照組的痊愈率分別為,83.3%、62.1%(P0.01),總有效率分別為98.6%、82.8%(P0.01)。結論短期靜脈高糖營養(yǎng)聯(lián)合胰島素治療妊娠劇吐較常規(guī)補液治療妊娠劇吐療效好。
[Abstract]:Objective to investigate the clinical efficacy of short-term intravenous hyperglycemia combined with insulin in the treatment of hyperemesis. Methods 130 patients with severe symptoms of hyperemesis were divided into two groups according to their wishes. 58 patients in the control group were treated with routine rehydration (intravenous infusion of glucose solution and glucose saline 3000ml daily, infusion of potassium chloride, vitamin C, vitamin B6 and so on). The 72 cases in the treatment group were treated with vitamin B1 intramuscular injection, except for the same intravenous fluid as the control group. The first 3 days were treated with intravenous high glucose nutrition for a short period of time. 5% glucose injection 500ml 50% glucose injection 4060 ml regular insulin 12 UU. Results after 3 days of treatment. The cure rates of the treatment group and the control group were 51.4 and 25.9m respectively, and the total effective rates were 100 / 77.6g / P 0.01g / L, respectively. After 5 days of treatment, the cure rates of the treatment group and the control group were 83.3% and 62.1%, respectively, and the total effective rate was 98.6%. Conclusion Short-term intravenous hyperglycemia combined with insulin is more effective than routine infusion in the treatment of hyperemesis.
【作者單位】: 河南省開封市婦產醫(yī)院;
【分類號】:R714.241
【正文快照】: 妊娠劇吐是在妊娠早期并發(fā)的、以頻繁惡心嘔吐,不能進食為主要表現的癥候群,病因至今不明。妊娠劇吐患者由于嚴重嘔吐、長期饑餓,引起水電解質紊亂,脂肪代謝的中間產物酮體積聚,尿中出現酮體,導致代謝性酸中毒。如不及時治療或治療不當,可導致WERNICK腦病、電解質紊亂引起心律
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