妊娠合并宮頸癌9例臨床分析
發(fā)布時(shí)間:2018-01-18 10:27
本文關(guān)鍵詞:妊娠合并宮頸癌9例臨床分析 出處:《浙江大學(xué)》2014年碩士論文 論文類(lèi)型:學(xué)位論文
更多相關(guān)文章: 妊娠 宮頸癌 臨床表現(xiàn) 診斷 治療
【摘要】:目的:分析妊娠合并宮頸癌的臨床特點(diǎn)、診斷和治療。 方法:回顧性分析自2000年1月至2014年1月我院收治的10例妊娠合并宮頸癌患者,其中1例診斷明確后即行剖宮產(chǎn)術(shù),術(shù)后自動(dòng)出院,另9例均接受不同治療,總結(jié)分析其臨床特點(diǎn)、診斷及治療方法。 結(jié)果:入選9例患者年齡23~42歲,平均年齡33.1歲。平均孕周18周,早孕5例(5/9),中孕2例(2/9),晚孕2例(2/9)。其中4例因發(fā)現(xiàn)宮頸異常入院,3例因陰道不規(guī)則流血入院,2例因陰道接觸性出血入院。9例患者均經(jīng)病理檢查診斷,主要病理類(lèi)型為宮頸鱗癌(8/9),4例Ib1期,4例Ib2期,另1例為宮頸腺鱗癌Ib1期。妊娠合并宮頸鱗癌患者年齡、臨床分期、細(xì)胞分化、腫瘤大小和宮頸深肌層浸潤(rùn)與非妊娠合并宮頸鱗癌之間差異非常顯著。宮頸鱗癌患者中4例腫瘤直徑4cm,4例腫瘤直徑≥4cm。4例孕早期患者選擇放棄胎兒直接接受規(guī)范化治療,行宮頸癌改良根治術(shù)。4例孕中、晚期患者行子宮下段剖宮產(chǎn)術(shù),其中1例剖宮產(chǎn)術(shù)后行化療,2例剖宮產(chǎn)術(shù)后行新輔助化療,再行宮頸癌改良根治術(shù),1例剖宮產(chǎn)術(shù)后直接行宮頸癌改良根治術(shù),術(shù)后建議放療。1例孕早期患者行宮頸癌改良根治術(shù)后續(xù)化療。孕中期患者2例中1例新生兒經(jīng)搶救存活,1例放棄;孕晚期2例新生兒均存活。 結(jié)論:妊娠合并宮頸鱗癌患者年齡、臨床分期、腫瘤大小和深肌層浸潤(rùn)與非妊娠合并宮頸鱗癌之間差異非常顯著;妊娠合并宮頸癌多為早期患者,治療應(yīng)個(gè)體化,對(duì)于中、晚孕期發(fā)現(xiàn)的宮頸癌可根據(jù)患者腫瘤分期、孕周、患者意愿等情況延遲治療至胎兒成熟。
[Abstract]:Objective: to analyze the clinical features, diagnosis and treatment of cervical cancer in pregnancy. Methods: from January 2000 to January 2014, 10 cases of pregnancy complicated with cervical cancer in our hospital were analyzed retrospectively. One case underwent cesarean section immediately after diagnosis, and was discharged automatically after operation. The other 9 cases were treated with different treatment, their clinical characteristics, diagnosis and treatment were summarized and analyzed. Results: the age of 9 patients was 2342 years old, with an average age of 33.1 years, an average gestational age of 18 weeks, an early pregnancy of 5 / 9, and a middle pregnancy of 2 / 9). Among them, 4 cases were admitted to hospital because of abnormal cervix. 3 cases were admitted to hospital because of irregular bleeding of vagina, 2 cases were admitted to hospital because of vaginal contact hemorrhage, 9 cases were diagnosed by pathological examination. The main pathological types were 4 cases of Ib1 stage 4 cases of Ib2 stage and 1 case of Ib1 stage of cervical adenosquamous carcinoma. Age, clinical stage and cell differentiation of pregnancy complicated with cervical squamous cell carcinoma were the main pathological types. There was a significant difference between the size of the tumor and the infiltration of the deep myometrium of the cervix and non-pregnant women with cervical squamous cell carcinoma. The diameter of the tumor was 4cm in 4 patients with cervical squamous cell carcinoma. 4 cases with tumor diameter 鈮,
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