本文關(guān)鍵詞：子癇前期患者血清胱抑素C檢測的臨床意義　出處：《新疆醫(yī)科大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 子癇前期 血清胱抑素C 妊娠結(jié)局

【摘要】：目的：探討血清胱抑素C的變化對子癇前期的病情預(yù)測及與妊娠結(jié)局的關(guān)系。。方法：回顧式研究，分析漢族、維吾爾族正常晚期妊娠者各50例，漢族、維吾爾族子癇前期輕度患者分別52、49例，子癇前期重度患者分別45、40例，測定血清胱抑素C、尿素氮、肌酐，白蛋白，24小時尿蛋白，血壓，比較子癇前期患者與正常對照組的胱抑素C水平差異，并對不同嚴(yán)重程度、不同妊娠結(jié)局的子癇前期患者的臨床資料、不良妊娠結(jié)果（包括子癇、羊水過少、胎兒窒息、胎盤早剝、胎兒生長受限、HELLP綜合征、子癇等）進(jìn)行分析比較。結(jié)果：本研究共納入人數(shù)286人，子癇前期患者186例，其中子癇前期患者輕度組101例，重度組85例，正常對照組孕婦100例。子癇前期患者的收縮壓、胱抑素C水平均顯著高于正常對照組，，差異有統(tǒng)計學(xué)意義（P0.05）；輕度組患者的收縮壓、胱抑素C值均顯著低于重度組,差異有統(tǒng)計學(xué)意義（P0.05）；漢族與維吾爾族子癇前期漢族胱抑素C差異無統(tǒng)計學(xué)意義（P0.05）；輕度組患者出現(xiàn)羊水過少、胎盤早剝、胎兒生長受限、HELLP綜合征的人數(shù)均低于重度組，差異均具有統(tǒng)計學(xué)意義；結(jié)局不良組患者的胱抑素C水平高于良好組,差異有統(tǒng)計學(xué)意義（P0.05）。結(jié)論：子癇前期患者的血清胱抑素C水平明顯上升，水平升高與嚴(yán)重程度相關(guān)，提示與不良妊娠結(jié)局有關(guān)。
[Abstract]:Objective: To investigate the changes of preeclampsia serum cystatin C in the prognosis and relationship with pregnancy outcome. Methods: retrospective study, analysis of the Han nationality, Uygur normal pregnancy in 50 cases, Han, Uygur patients with mild preeclampsia were 52,49 cases, patients with severe preeclampsia were 45,40 cases, serum cystatin C, urea nitrogen, creatinine, albumin, 24 hours urine protein, blood pressure difference, Cystatin C levels in patients with preeclampsia compared with normal control group, and the difference of the severity of the clinical data of different pregnancy outcomes in preeclampsia patients, adverse pregnancy outcomes (including eclampsia, oligohydramnios, fetal asphyxia, placental abruption, fetal growth limited, HELLP syndrome, eclampsia, etc.) were analyzed and compared. Results: the study included a total number of 286 people, 186 cases of patients with preeclampsia, including patients with mild preeclampsia group 101 cases, 85 in severe group Cases of normal pregnant women in the control group. 100 cases of preeclampsia patients with systolic blood pressure, serum cystatin C levels were significantly higher than the normal control group, the difference was statistically significant (P0.05); mild group, systolic blood pressure, serum cystatin C values were significantly lower than those in severe group, the difference was statistically significant (P0.05); no statistical significance of Han and Uygur Han preeclampsia cystatin C (P0.05); the difference of patients with mild oligohydramnios, placental abruption, fetal growth restriction, the number of HELLP syndrome were lower than that in severe group, the difference was statistically significant; adverse outcomes in patients with cystatin C level is higher than that of group, the difference was statistically significant (P0.05). Conclusion: eclampsia in patients with serum cystatin C levels increased obviously, elevated levels correlated with the severity of that associated with adverse pregnancy outcomes.

【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R714.244

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