【摘要】：目的:研究分析活血利膽退黃經(jīng)驗(yàn)方輔助常規(guī)西醫(yī)療法治療巨細(xì)胞病毒(CMV)感染相關(guān)膽汁淤積性肝炎患兒的臨床效果。方法:選取本院收治的123例CMV相關(guān)膽汁淤積性肝炎患兒,隨機(jī)分為中西醫(yī)組62例和西醫(yī)組61例,兩組均給予更昔洛韋抗病毒、保肝護(hù)肝、維生素、熊去氧膽酸等常規(guī)治療,中西醫(yī)組加用活血利膽退黃經(jīng)驗(yàn)方進(jìn)行輔助治療,兩組患兒的療程均為5周,觀察臨床指標(biāo)及治療效果差異。結(jié)果:治療后中西醫(yī)組的TBIL、DBIL、TBA值均顯著的低于西醫(yī)組患兒(P0.05),中西醫(yī)組的CVM-DNA轉(zhuǎn)陰率59.68%顯著的高于對(duì)照組52.46%(P0.05)。中西醫(yī)組患兒的黃疸消退時(shí)間、肝臟回縮時(shí)間、脾臟回縮時(shí)間均顯著的短于西醫(yī)組患兒(P0.05)。治療后中西醫(yī)組的中醫(yī)證候積分值顯著的低于西醫(yī)組患兒且差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。治療后中西醫(yī)組患兒的總有效率(98.39%)高于西醫(yī)組的(95.08%)但差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:活血利膽退黃經(jīng)驗(yàn)方輔助常規(guī)西醫(yī)療法治療CMV感染相關(guān)膽汁淤積性肝炎能夠盡快緩解患兒的臨床癥狀、體征及指標(biāo)恢復(fù),是對(duì)西醫(yī)療法的重要補(bǔ)充。
[Abstract]:Objective: to study and analyze the clinical effect of Huoxue Lidan Tuihuang recipe combined with conventional western medicine in the treatment of children with cholestatic hepatitis associated with Cytomegalovirus (CMV) infection. Methods: 123 children with CMV-related cholestatic hepatitis were randomly divided into traditional Chinese and western medicine group (n = 62) and western medicine group (n = 61). Both groups were treated with ganciclovir antivirus, liver protection and liver protection, vitamins and ursodeoxycholic acid. In the traditional Chinese and western medicine group, Huoxue Lidan antipyretic prescription was used for auxiliary treatment. The course of treatment of the two groups was 5 weeks. The clinical indexes and therapeutic effect were observed. Results: after treatment, the TBIL,DBIL, TBA value in the traditional Chinese and western medicine group was significantly lower than that in the western medicine group (P 0.05). The negative conversion rate of CVM-DNA in the traditional Chinese and western medicine group was 59.68%, which was significantly higher than that in the control group (52.46%). The jaundice regression time, liver retraction time and spleen retraction time in the Chinese and western medicine group were significantly shorter than those in the western medicine group (P 0.05). After treatment, the score of TCM syndromes in the traditional Chinese and western medicine group was significantly lower than that in the western medicine group, and the difference was statistically significant (P 0.05). After treatment, the total effective rate of children in Chinese and western medicine group (98.39%) was higher than that in western medicine group (95.08%), but there was no significant difference (P 0.05). Conclusion: Huoxue Lidan Tuihuang prescription can relieve the clinical symptoms, signs and indexes of children with CMV infection related cholestasis hepatitis as soon as possible, which is an important supplement to western medicine therapy.
【作者單位】： 武漢市婦女兒童醫(yī)療保健中心;黃石市婦幼保健院;
【分類號(hào)】：R725.1

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