【摘要】：目的了解亳州地區(qū)兒童急性呼吸道感染病例病原體的分布情況。方法采用間接免疫熒光法對該院2015年4月至2016年3月診治的2 846例急性呼吸道感染患兒外周血標本進行腺病毒、流感病毒A、流感病毒B、呼吸道合胞病毒、副流感病毒、肺炎支原體、肺炎衣原體、嗜肺軍團菌檢測,了解患兒病原體的分布情況。結果 2 846例患兒病原體檢測陽性1 161例(40.8%),其中檢出率最高的前3位病原體分別是肺炎支原體[470例(16.5%)]、流感病毒A[252例(8.9%)]及呼吸道合胞病毒[117例(4.1%)],并有79例混合感染(2.8%)。隨年齡增加病原體檢出率呈下降趨勢(χ~2=20.724,P=0.000 1)。嬰幼兒感染以呼吸道合胞病毒為主(11.2%),學齡前及學齡兒童以肺炎支原體感染為主(15.2%~25.4%)。冬季病原體感染檢出率最高(57.7%),夏季最低(22.5%)。結論亳州地區(qū)急性呼吸道感染病原體流行病學分布隨年齡、季節(jié)而不同,嬰幼兒感染率高于其他年齡段,肺炎支原體、流感病毒A及呼吸道合胞病毒是亳州地區(qū)兒童急性呼吸道感染的主要病原體,秋冬季高發(fā)應注意加強預防感染。
[Abstract]:Objective to investigate the distribution of pathogens in children with acute respiratory tract infection (ARI) in Bozhou. Methods adenovirus, influenza A, influenza B, respiratory syncytial virus and parainfluenza virus were detected by indirect immunofluorescence in peripheral blood samples of 2846 children with acute respiratory tract infection from April 2015 to March 2016. Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila detection, to understand the distribution of pathogens in children. Results 1 161 cases (40.8%) were positive for pathogen detection in 2 846 cases, among which the first 3 pathogens were Mycoplasma pneumoniae [470 cases (16.5%)], and the highest positive rate was mycoplasma pneumoniae [470 cases (16.5%)]. Influenza virus A [252 cases (8.9%)] and respiratory syncytial virus [117 cases (4.1%)], and 79 cases of mixed infection (2.8%). The detection rate of pathogens decreased with age (蠂 ~ 2, 20.724, P < 0.0001). Respiratory syncytial virus was the main infection in infants (11.2%), Mycoplasma pneumoniae infection was predominant in preschool and school-age children (15.2% / 25.4%). The detection rate of pathogen infection was the highest (57.7%) in winter and the lowest (22.5%) in summer. Conclusion the distribution of pathogens of acute respiratory tract infection varies with age and season in Bozhou. The infection rate of infants is higher than that of mycoplasma pneumoniae in other age groups. Influenza virus A and respiratory syncytial virus are the main pathogens of acute respiratory tract infection in Bozhou area. The high incidence of influenza A and respiratory syncytial virus in autumn and winter should be strengthened to prevent infection.
【作者單位】： 安徽省亳州市人民醫(yī)院兒科;
【分類號】：R725.6

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