【摘要】：目的:探討原發(fā)性腎病綜合征(NS)激素敏感頻復(fù)發(fā)患兒與肺炎支原體感染的關(guān)系。方法:選取原發(fā)性腎病綜合征激素敏感頻復(fù)發(fā)患兒同時合并急性呼吸道感染者共35例,根據(jù)結(jié)果分肺炎支原體(MP)感染患兒為觀察組,其他感染患兒為對照組,觀察患兒的臨床特征,對比治療前后的各項檢驗指標(biāo)的變化,包括24小時尿蛋白定量(24 h-Upro)、尿素氮(BUN)、血肌酐(Scr)、血漿白蛋白(Alb)、總膽固醇(Chol)等。統(tǒng)計分析兩組患兒的治療療效。結(jié)果:兩組治療后各項臨床生化指標(biāo)均有明顯改善,差異有統(tǒng)計學(xué)意義(P≤0.01)。治療后24 h尿蛋白定量下降明顯,從數(shù)值上看觀察組較對照組下降更明顯。觀察組18例患兒治療有效15例,其中完全緩解9例,部分緩解6例;對照組17例患兒治療有效14例,其中完全緩解6例,部分緩解8例。結(jié)論:急性呼吸道感染誘發(fā)的激素敏感頻復(fù)發(fā)NS患兒經(jīng)過治療后,多數(shù)能得到緩解,蛋白尿、低蛋白血癥、高脂血脂、腎功能均恢復(fù)較快,預(yù)后好,其中應(yīng)用阿奇霉素治療MP感染誘發(fā)的激素敏感頻復(fù)發(fā)的NS患兒療效更顯著。
[Abstract]:Objective: to investigate the relationship between (NS) hormone-sensitive relapse and Mycoplasma pneumoniae infection in children with primary nephrotic syndrome (PNS). Methods: a total of 35 children with primary nephrotic syndrome complicated with acute respiratory tract infection were selected. According to the results, children with mycoplasma pneumoniae (MP) infection were divided into observation group and control group. The clinical features of the patients were observed, and the changes of the test indexes before and after treatment were compared, including 24-hour urinary protein quantity (24 h-Upro), blood urea nitrogen (BUN), serum creatinine (Scr), plasma albumin (Alb), total cholesterol (Chol), and so on. The therapeutic effects of the two groups were analyzed statistically. Results: the clinical biochemical indexes of the two groups were obviously improved after treatment, the difference was statistically significant (P 鈮，

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