C反應(yīng)蛋白、前清蛋白聯(lián)合白細(xì)胞計(jì)數(shù)在新生兒感染性疾病中的診斷及應(yīng)用
發(fā)布時(shí)間：2019-01-06 17:33
【摘要】：目的探討C反應(yīng)蛋白(CRP)、血清前清蛋白(PA)及白細(xì)胞計(jì)數(shù)(WBC)聯(lián)合檢測(cè)對(duì)于新生兒感染性疾病的診斷及臨床應(yīng)用價(jià)值。方法收集187例足月新生患兒,其中92例細(xì)菌感染患兒作為感染組,95例非感染性疾病患兒作為非感染組,檢測(cè)CRP、PA及WBC分別在兩組中所占異常率;比較單項(xiàng)及聯(lián)合應(yīng)用的敏感度和特異度及假陽(yáng)性率和假陰性率;觀察比較感染組患兒3種指標(biāo)治療前后的變化情況。結(jié)果感染組新生兒的CRP、PA及WBC異常率均明顯高于非細(xì)菌感染性疾病組(P0.05);聯(lián)合檢測(cè)CRP+PA+WBC較單獨(dú)檢測(cè)CRP、PA、WBC的靈敏度和特異度高;治療后,感染組新生兒CRP水平顯著降低,PA水平明顯升高,WBC計(jì)數(shù)恢復(fù)正常(P0.05)。結(jié)論 CRP、PA及WBC聯(lián)合檢測(cè)對(duì)早期診斷新生兒細(xì)菌性感染具有重要的臨床價(jià)值。
[Abstract]:Objective to investigate the diagnostic and clinical value of C reactive protein (CRP),) prealbumin (PA) and white blood cell count (WBC) in neonatal infectious diseases. Methods the abnormal rates of CRP,PA and WBC were detected in 187 full-term newborns, including 92 cases of bacterial infection as infection group and 95 cases of non-infectious disease as non-infection group. The sensitivity, specificity, false positive rate and false negative rate of single and combined use were compared, and the changes of the three indexes before and after treatment were observed and compared. Results the abnormal rates of CRP,PA and WBC in infected neonates were significantly higher than those in non-bacterial infectious diseases (P0.05), and the sensitivity and specificity of combined detection of CRP PA WBC were higher than those of CRP,PA,WBC alone. After treatment, the level of CRP decreased significantly, the level of PA increased significantly and the WBC count returned to normal in infected group (P0.05). Conclusion the combined detection of CRP,PA and WBC has important clinical value in the early diagnosis of neonatal bacterial infection.
【作者單位】： 重慶市北碚區(qū)婦幼保健院;
【分類號(hào)】：R722.13
本文編號(hào)：2403105
[Abstract]:Objective to investigate the diagnostic and clinical value of C reactive protein (CRP),) prealbumin (PA) and white blood cell count (WBC) in neonatal infectious diseases. Methods the abnormal rates of CRP,PA and WBC were detected in 187 full-term newborns, including 92 cases of bacterial infection as infection group and 95 cases of non-infectious disease as non-infection group. The sensitivity, specificity, false positive rate and false negative rate of single and combined use were compared, and the changes of the three indexes before and after treatment were observed and compared. Results the abnormal rates of CRP,PA and WBC in infected neonates were significantly higher than those in non-bacterial infectious diseases (P0.05), and the sensitivity and specificity of combined detection of CRP PA WBC were higher than those of CRP,PA,WBC alone. After treatment, the level of CRP decreased significantly, the level of PA increased significantly and the WBC count returned to normal in infected group (P0.05). Conclusion the combined detection of CRP,PA and WBC has important clinical value in the early diagnosis of neonatal bacterial infection.
【作者單位】： 重慶市北碚區(qū)婦幼保健院;
【分類號(hào)】：R722.13
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