【摘要】：目的探究口服鋅制劑對輪狀病毒感染所致腸炎患兒的治療效果,以及治療后3、6個月內(nèi)患兒病情復(fù)發(fā)情況。方法選取2014年2月-2016年6月于醫(yī)院接受治療的162例患兒為研究對象,按照隨機(jī)數(shù)表法平均分成觀察組與對照組,每組各81例;對照組接受常規(guī)治療方案,觀察組在常規(guī)治療基礎(chǔ)上添加口服鋅制劑治療,比較兩組患兒治療效果及治療前后身體功能性損傷情況,統(tǒng)計并分析兩組患兒治療后腸炎復(fù)發(fā)例數(shù)以及安全性評分。結(jié)果觀察組患兒接受口服鋅制劑治療后中重度脫水、肝臟功能以及呼吸道損傷癥狀均有所好轉(zhuǎn),患兒患病例數(shù)明顯減少,而對照組患兒治療后效果不顯著,減少的例數(shù)不明顯;治療后兩組患兒治療效果差異較大,其中觀察組患兒顯效率明顯高于對照組,兩組治療效果比較,差異有統(tǒng)計學(xué)意義(χ~2=6.438,P0.05);病情復(fù)發(fā)情況顯示,觀察組及對照組患兒的腹瀉嘔吐現(xiàn)象隨著時間的延長逐漸減少,但對照組患兒在治療后1、3、6個月三個時間段內(nèi)腹瀉以及嘔吐的復(fù)發(fā)例數(shù)均比觀察組多,觀察組在治療后6個月的電話隨訪發(fā)現(xiàn)嘔吐復(fù)發(fā)例數(shù)僅有2例(2.4%),而腹瀉復(fù)發(fā)例數(shù)僅有1例(1.2%),常規(guī)治療添加口服鋅制劑治療輪狀病毒較常規(guī)治療有效,治療后復(fù)發(fā)率低,差異有統(tǒng)計學(xué)意義(χ~2=6.217,P0.05);安全性方面,觀察組安全評分(93.13±4.99)分較對照組(75.49±8.41)分高。結(jié)論口服鋅制劑對輪狀病毒感染所致腸炎患兒的治療效果顯著,能有效降低患兒治療后病情復(fù)發(fā)率,且能有效減輕病毒感染致腸炎患兒復(fù)發(fā)時的腹瀉、嘔吐癥狀。
[Abstract]:Objective to investigate the therapeutic effect of oral zinc preparation on enteritis caused by rotavirus infection and its recurrence in 3 months and 6 months after treatment. Methods 162 children who were treated in hospital from February 2014 to June 2016 were randomly divided into observation group (n = 81) and control group (n = 81). The patients in the control group were treated with routine treatment regimen, and the patients in the observation group were treated with oral zinc preparation on the basis of routine treatment. The therapeutic effect and functional injury of the body before and after treatment were compared between the two groups. The recurrent cases of enteritis and safety score were analyzed and analyzed in the two groups. Results after treatment with oral zinc preparation, the liver function and respiratory tract injury symptoms were improved, and the number of patients in the observation group was significantly reduced, while the effect of the treatment in the control group was not significant, and the number of cases decreased. There was a significant difference between the two groups after treatment, among which the effective rate of the observation group was significantly higher than that of the control group, and the difference between the two groups was statistically significant (蠂 ~ (2) 6.438 (P0.05). The recurrence of the disease showed that the diarrhea and vomiting in the observation group and the control group gradually decreased with the prolongation of time, but the number of the diarrhea and vomiting in the control group was more than that in the observation group in the period of 3 months, 6 months after treatment, and the incidence of diarrhea and vomiting in the control group was higher than that in the control group. In the observation group, only 2 cases (2.4%) of vomiting recurred and 1 case (1.2%) of diarrhea recurred 6 months after treatment. Routine treatment with oral zinc preparation was more effective than conventional treatment. The recurrence rate was low after treatment, and the difference was statistically significant (蠂 ~ 2 ~ (6.217) P 0.05). The safety score of the observation group (93.13 鹵4.99) was higher than that of the control group (75.49 鹵8.41). Conclusion the effect of oral zinc preparation on children with enteritis caused by rotavirus infection is remarkable. It can effectively reduce the relapse rate of children with enteritis caused by rotavirus infection, and can effectively reduce the symptoms of diarrhea and vomiting in children with enteritis caused by virus infection.
【作者單位】： 儋州市第一人民醫(yī)院兒科;
【分類號】：R725.1

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 賈晉平;;鋅制劑輔助治療小兒反復(fù)呼吸道感染療效觀察[J];山東醫(yī)藥;2008年38期

2 潘合蘭;;國內(nèi)鋅制劑及其在兒科的應(yīng)用[J];廣西醫(yī)學(xué);1992年04期

3 董俊紅;;補(bǔ)鋅制劑治療小兒腹瀉的臨床效果觀察[J];環(huán)球中醫(yī)藥;2013年S2期

4 郭愛平;;關(guān)于鋅制劑治療小兒腹瀉的療效觀察[J];中國醫(yī)藥指南;2013年25期

5 楊懷志;;口服鋅制劑佐治嬰幼兒急性腹瀉的臨床分析[J];中國當(dāng)代醫(yī)藥;2011年18期

6 吳方明;;鋅制劑輔助治療小兒腹瀉病的效果觀察[J];中國當(dāng)代醫(yī)藥;2014年14期

7 付溥和;徐丹;;鋅制劑輔助治療嬰幼兒毛細(xì)支氣管炎的療效觀察[J];中國醫(yī)院用藥評價與分析;2013年12期

8 丁先露;鋅制劑“維寶康”治療兒童缺鋅綜合征的臨床研究[J];廣東微量元素科學(xué);1996年03期

9 王麗;鋅制劑與促菌生聯(lián)合應(yīng)用治療腹瀉40例分析[J];洛陽醫(yī)專學(xué)報;2001年03期

10 ;鋅制劑治療小兒厭食臨床觀察[J];安徽醫(yī)學(xué);1993年06期

相關(guān)重要報紙文章 前1條

1 余志平;鋅制劑：新用途何其多[N];醫(yī)藥經(jīng)濟(jì)報;2000年

，

本文編號：2391034