【摘要】：[目的]分析過敏性紫癜與EB病毒感染的關(guān)系,為以后臨床診斷及治療提供依據(jù)。[方法]用回顧性調(diào)查的方法,收集2014年2月至2016年1月住院診斷為HSP患兒的臨床資料和EB病毒載量測定的結(jié)果,根據(jù)臨床特點(diǎn)把患兒分為單純型、腹型、腎型、關(guān)節(jié)型、混合型,對發(fā)病年齡及性別、住院天數(shù)、發(fā)病季節(jié)、EB病毒載量及EB病毒陽性比進(jìn)行統(tǒng)計(jì)分析,所有數(shù)據(jù)經(jīng)統(tǒng)計(jì)學(xué)方法處理。[結(jié)果]在248例HSP患兒中,男性147例(59. 3%),女性101例(40. 7%)。年齡為2~16歲,平均年齡8. 89±2.89歲,1歲到3歲4例,3歲到6歲58例,7歲至10歲107例,≥11歲79例。發(fā)病季節(jié),春季(2-4 月)76 例(30.6%),夏季(5-7 月)36 例(14.5%),秋季(8-10 月)56 例(22.6%),冬季(11 月-1 月)79 例(32. 3%),不同季節(jié)EBV陽性檢出率差異有統(tǒng)計(jì)學(xué)意義,春冬季明顯高于秋季。其中單純型35例(14. 1%),腹型37例(14. 9%),腎型74例(29. 8%),關(guān)節(jié)型36例(14.5%),混合型66例(26.7%)。EB病毒陽性共105例,陽性率42%。病毒載量范圍為4. 08×102-8.6×105拷貝/ml,其中4. 0X 102-4. 0X 103的有 51 人(48.6%),4.0X 103-4. 0X 104拷貝/ml的有 45 人(42. 9%),4. 0× 104-4. 0× 105拷貝/ml 的有 8 人(7. 6%),4. 0× 105-4. 0× 106拷貝/ml的有1人(0.9%),病毒載量介于4. 0X 102-4. 0×103拷貝/ml所占比例最大。相對應(yīng)地,EB病毒感染單純型14例(13.3%),腹型16例(15.2%),腎型28例(26.6%),關(guān)節(jié)型17例(16. 2%),混合型30例(28. 7%),各類型間EB病毒感染陽性比無顯著差異。HSP住院天數(shù)3~43天,平均住院天數(shù)10.91±6.64天。EB病毒陽性患兒的住院天數(shù)(17.12天)明顯高于陰性患兒(12.96天)。[結(jié)論]1、HSP發(fā)病男童高于女童,以學(xué)齡兒童多見,以春冬季為主。2、HSP患兒EB病毒陽性檢出率高,EB病毒陽性可致患兒住院時(shí)間延長。3、不同季節(jié)HSP患兒EB陽性檢出率不同,春冬季明顯高于秋季,應(yīng)加強(qiáng)個人衛(wèi)生以預(yù)防EB病毒感染。
[Abstract]:Objective: to analyze the relationship between Henoch-Schonlein purpura and EB virus infection in order to provide basis for clinical diagnosis and treatment. [methods] from February 2014 to January 2016, the clinical data and the results of EB viral load determination in hospitalized children with HSP were collected and classified into simple type, abdominal type, renal type and articular type by retrospective investigation. The age and sex of the disease, the days of hospitalization, the season of onset, the load of EB virus and the positive ratio of EB virus were statistically analyzed. All the data were processed by statistical method. [results] among 248 cases of HSP, 147 cases (59. 7%) were male. (3%), 101 female (40. 5%). 7%) The average age is 8. 5%. 89 鹵2.89 years old, 1 to 3 years old in 4 cases, 3 to 6 years old in 58 cases, 7 to 10 years old in 107 cases, 鈮，

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