【摘要】：目的分析小兒急性腎小球腎炎合并尿路感染患者的病原學(xué)特點(diǎn)和相關(guān)實(shí)驗(yàn)室指標(biāo)變化。方法選取醫(yī)院2014年10月-2016年5月收治的254例小兒急性腎小球腎炎病例,根據(jù)是否合并尿路感染分為尿路感染組130例和單純腎炎組124例,比較兩組在實(shí)驗(yàn)室檢測指標(biāo)上的差異,并對尿路感染組進(jìn)行病原菌鑒定,分析病原菌的分布情況。結(jié)果急性腎小球腎炎患者合并尿路感染130例,感染率51.18%,尿路感染組患兒年齡、性別、高血壓、下肢浮腫、血尿、尿蛋白水平、紅細(xì)胞形態(tài)、顆粒管型與單純腎炎患兒相比無統(tǒng)計(jì)學(xué)差異,尿路感染組患兒尿頻74.62%、尿急76.15%、尿痛79.23%、腎區(qū)疼痛44.62%、小腹疼痛45.38%、高燒46.92%、白細(xì)胞計(jì)數(shù)升高81.54%、細(xì)胞管型54.62%顯著高于單純腎炎組(P0.05);急性腎小球腎炎合并尿路感染患兒共檢測出病原菌174株,其中革蘭陰性桿菌120株占68.97%,以大腸埃希菌為主;革蘭陽性菌48株占27.59%,以屎腸球菌、糞腸球菌為主;真菌6株占3.45%。結(jié)論急性腎小球腎炎合并尿路感染并無特異性臨床表現(xiàn),早期進(jìn)行實(shí)驗(yàn)室指標(biāo)聯(lián)合檢測極為重要,且急性腎小球腎炎合并尿路感染主要病菌分布廣泛,以革蘭陰性桿菌感染為主。
[Abstract]:Objective to analyze the etiological characteristics and related laboratory indexes of children with acute glomerulonephritis complicated with urinary tract infection. Methods 254 children with acute glomerulonephritis from October 2014 to May 2016 were divided into urinary tract infection group (130 cases) and simple nephritis group (124 cases). The pathogens of urinary tract infection group were identified and the distribution of pathogens was analyzed. Results 130 patients with acute glomerulonephritis complicated with urinary tract infection, the infection rate was 51.18.The age, sex, hypertension, edema of lower extremities, hematuria, urinary protein level, erythrocyte morphology in urinary tract infection group. There was no statistical difference between the granular tube type and simple nephritis. In the urinary tract infection group, the urinary frequency was 74.62, the urination was 76.15, the urinal pain was 79.23, the renal area pain was 44.62, the lower abdomen pain was 45.38 and the fever was 46.92. The white blood cell count increased by 81.54 and 54.62% of the cells were significantly higher than that of the simple nephritis group (P0.05). 174 strains of pathogenic bacteria were detected in children with acute glomerulonephritis complicated with urinary tract infection, among which 120 strains of Gram-negative bacilli accounted for 68.97 strains, mainly Escherichia coli, 48 strains of Gram-positive bacteria accounted for 27.59%, mainly Enterococcus faecium and Enterococcus faecalis. 6 strains of fungi accounted for 3.45%. Conclusion there is no specific clinical manifestation in acute glomerulonephritis complicated with urinary tract infection. It is very important to test the laboratory indexes in the early stage, and the main bacteria of acute glomerulonephritis complicated with urinary tract infection are widely distributed. Gram-negative bacilli were the main infection.
【作者單位】： 鄭州大學(xué)附屬鄭州中心醫(yī)院高新兒科;鄭州大學(xué)附屬鄭州中心醫(yī)院兒童康復(fù)科;鄭州大學(xué)附屬鄭州中心醫(yī)院高新神經(jīng)內(nèi)科;
【分類號(hào)】：R726.9

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