【摘要】：目的探究新生兒科住院患兒醫(yī)院感染的病原學(xué)特點及危險因素,進(jìn)一步形成有效預(yù)防對策。方法選擇2015年10月-2016年10月醫(yī)院新生兒科收治的3370例新生兒作為研究對象,回顧分析胎齡、出生體質(zhì)量、侵入性操作、感染前使用抗菌藥物或激素、喂養(yǎng)方式、分娩方式、住院時間等資料,探究病原學(xué)特點,并對新生兒院內(nèi)感染的危險因素進(jìn)行單因素及多因素分析,形成有效預(yù)防對策。結(jié)果 3370例新生兒共發(fā)生醫(yī)院感染60例,感染率為1.78%;共培養(yǎng)病原菌60株,其中革蘭陰性菌38株占63.33%,以肺炎克雷伯菌為主,革蘭陽性菌19株占31.67%,以葡萄球菌為主,真菌3株占5.00%;多因素logistic研究結(jié)果顯示,胎齡37周、非自然分娩、出生體質(zhì)量2500g、腸外營養(yǎng)、侵入性操作、住院時間長以及感染前使用抗菌藥物或激素等,是新生兒院內(nèi)感染的獨立危險因素。結(jié)論通過對新生兒院內(nèi)感染臨床資料分析,探究病原學(xué)特點和危險因素,總結(jié)有效預(yù)防措施,以減少新生兒院內(nèi)感染。
[Abstract]:Objective to explore the etiological characteristics and risk factors of nosocomial infection in neonatal hospitalized children and to form effective preventive measures. Methods from October 2015 to October 2016, 3370 newborns were selected and analyzed retrospectively, such as gestational age, birth weight, invasive operation, use of antibiotics or hormones before infection, feeding mode and delivery mode. In order to find out the etiological characteristics and analyze the risk factors of nosocomial infection in neonates, the effective preventive measures were formed. Results there were 60 cases of nosocomial infection in 3370 newborns, and the infection rate was 1.78%. Among the 60 strains of pathogenic bacteria cultured, 38 were Gram-negative bacteria (63.33), mainly Klebsiella pneumoniae, 19 Gram-positive bacteria (31.67m), mainly Staphylococcus (Staphylococcus), and 3 fungi (5.00%). The results of multivariate logistic study showed that gestational age of 37 weeks, unnatural delivery, birth weight of 2500g, parenteral nutrition, invasive operation, length of stay in hospital and use of antibiotics or hormones before infection were independent risk factors of nosocomial infection. Conclusion by analyzing the clinical data of neonatal nosocomial infection, the etiological characteristics and risk factors are explored, and effective preventive measures are summarized to reduce neonatal nosocomial infection.
【作者單位】： 寧波市婦女兒童醫(yī)院新生兒科;
【基金】：浙江省醫(yī)藥衛(wèi)生科技計劃基金資助項目(2013KYB240)
【分類號】：R197.323;R722.13
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本文編號：2339666