【摘要】：目的：觀察從龍溫膽湯治療小兒哮喘慢性持續(xù)期(濕滯痰濁型)的臨床療效。 方法：將64例哮喘慢性持續(xù)期(濕滯痰濁型)患兒隨機分為治療組及對照組各32例,治療組給予從龍溫膽湯口服,對照組給予丙酸倍氯米松氣霧劑治療,以3個月為一療程。觀察兩組患兒臨床療效及工gE與CD4+、CD8+的變化。 結(jié)果： 治療3個月后表明：治療組綜合療效90.63%,而對照組綜合療效為83.33%,兩組無顯著差異：治療組改善中醫(yī)證候療效優(yōu)于對照組,P0.05；在減輕哮喘患兒癥狀、體征總積分方面,治療組優(yōu)于對照組,P0.05；治療組比對照組更能有效地降低IgE及CD4+水平,使CD8+含量上升,P0.05。 結(jié)論： 1.臨床實驗表明從龍溫膽湯能夠明顯改善哮喘慢性持續(xù)期濕滯痰濁證 患兒的癥狀及肺部體征 2.從龍溫膽湯能有效的降低CD4+及IgE水平,升高CD8+,這也可能是從龍溫膽湯治療哮喘的機制之一 3.治療期間患兒無不良反應(yīng),藥物安全可靠。
[Abstract]:Objective: to observe the clinical effect of Zhonglong Wendan decoction (ZWT) on chronic asthmatic period (dampness stagnation and phlegm turbid type). Methods: 64 children with chronic asthma (dampness stagnation and phlegm turbid type) were randomly divided into treatment group (n = 32) and control group (n = 32). The treatment group was treated with Huilong Wendan decoction and the control group was treated with beclomethasone propionate aerosol for 3 months. The clinical effect and the changes of gE, CD4 and CD8 in the two groups were observed. Results: after 3 months of treatment, the comprehensive curative effect of the treatment group was 90.63 and that of the control group was 83.33. There was no significant difference between the two groups: the curative effect of improving TCM syndrome in the treatment group was better than that in the control group, P 0.05; The treatment group was superior to the control group (P0.05) in alleviating the symptoms and signs of asthmatic children, and the treatment group was more effective than the control group in reducing the levels of IgE and CD4 and increasing the content of CD8 (P0.05). Conclusion: 1. The clinical experiment shows that Zhonlong Wendan decoction can obviously improve the symptoms and pulmonary signs of children with chronic persistent asthmatic dampness stagnation and phlegm turbidity syndrome. Zulong Wendan decoction can effectively reduce the levels of CD4 and IgE and increase CD8, which may also be one of the mechanisms of treatment of asthma from long Wendan decoction. There were no adverse reactions during the treatment and the drugs were safe and reliable.
【學(xué)位授予單位】：黑龍江中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R272

【參考文獻】

相關(guān)期刊論文 前10條

1 王和清;;小兒體質(zhì)與哮喘關(guān)系探微[J];中醫(yī)藥臨床雜志;2007年01期

2 余啟梅,辛建保;哮喘緩解期聯(lián)用烏體林斯和黃芪注射液等穴位注射控制哮喘發(fā)作的臨床觀察[J];安徽醫(yī)學(xué);2003年02期

3 季紹良,張秋云;哮喘治療經(jīng)驗[J];中國醫(yī)藥學(xué)報;1996年06期

4 張芬蘭,劉春梅;柴樸湯加味治療咳嗽變異性哮喘[J];長春中醫(yī)學(xué)院學(xué)報;2003年04期

5 栗慶林;從肝從風論治支氣管哮喘[J];光明中醫(yī);2004年06期

6 高軍寧;劉淑霞;;溫膽湯的源流、類方、方證及臨床應(yīng)用[J];甘肅中醫(yī)學(xué)院學(xué)報;2009年05期

7 殷莉波;三子平喘湯治療小兒哮喘52例療效觀察[J];甘肅中醫(yī);2003年07期

8 陸愛平;穴埋藥線治療支氣管哮喘68例[J];黑龍江中醫(yī)藥;2001年05期

9 曾德友;分型論治急性支氣管哮喘78例[J];湖南中醫(yī)藥導(dǎo)報;2000年07期

10 劉自力;吳兆利;;培土生金法治療支氣管哮喘(緩解期)35例臨床觀察[J];中醫(yī)藥導(dǎo)報;2006年01期

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