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健康教育聯(lián)合口服補液鹽治療兒童直立性低血壓的療效評價

發(fā)布時間:2018-10-26 21:03
【摘要】:目的研究健康教育聯(lián)合口服補液鹽治療兒童直立性低血壓(OH)的療效以及對直立傾斜試驗(HUTT)結(jié)果的影響。 方法對2009年-10月~2012年-01月在中南大學(xué)湘雅二醫(yī)院兒童暈厥?崎T診就診或住院的行HUTT診斷為OH兒童51例,男30例,女21例,年齡4~16歲(平均9.82±2.96歲)。給予健康教育及口服補液鹽(ORS)治療,治療30d后11例復(fù)查HUTT.采用SPSS16.0軟件進行統(tǒng)計學(xué)分析,使用t檢驗。 結(jié)果30d后OH兒童回院復(fù)查11例,其余兒童經(jīng)電話聯(lián)系不能堅持治療方案或不能按時復(fù)診而剔除統(tǒng)計。11例復(fù)查HUTT顯示:①SBP0(平臥位時收縮壓)比較:治療前與治療后比較差異無統(tǒng)計學(xué)意義(106.27±10.82mmHg vs103.27±8.91mmHg,t=0.710,P0.05)。②SBP3min(站立位3min時收縮壓)比較:治療后比治療前升高(104.91±9.92mmHg vs90.55±18.06mmHg,t=-2.311,P0.05)。③DBP0(平臥位時舒張壓)比較:治療前后比較差異無統(tǒng)計學(xué)意義(70.45±8.89mmHg vs67.27±11.79mmHg,t=0.715,P0.05).④DBP3min(站立位3min時舒張壓)比較:治療后較治療前升高(70.00±6.15mmHg vs55.18±12.77mmHg,t=-3.469,P0.05).⑤△SBP=SBPO-SBP3min(HUTT3min收縮壓下降值)比較:治療后SBP下降幅度較治療前明顯減小(-1.64±6.23mmHg vs15.73±15.10mmHg,t=3.525,P0.05).⑥△DBP=DBPO-DBP3min(HUTT3min舒張壓下降值)比較:治療后DBP下降幅度較治療前明顯減小(-2.73±11.10mmHg vs15.27±11.24mmHg,t=3.778,P0.05).⑦HRO(HUTT開始前平臥位時心率)比較:治療前后HR比較無統(tǒng)計學(xué)差異(84.73±14.46次/min vs85.73±9.65次/min,t=-0.191,P0.05);HR3min(HUTT開始后3min時心率)比較:治療前后HR3min比較差異無統(tǒng)計學(xué)意義(94.27±15.96次/min vs105.18±6.69次/min,t=-2.090,P0.05)。⑧不同性別治療前SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、△SBP以及△DBP比較:兩者比較均無統(tǒng)計學(xué)差異(P0.05);⑨不同性別治療后SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、ASBP以及ADBP比較:△SBP男性下降幅度較女性下降小(-6.00±2.24mmHg vs2.00±6.23mmHg,t=-2.709,P0.05);而SBP0、SBP3min、DBP0、DBP3min、HR0、HR3min、△DBP男性與女性比較差異均無統(tǒng)計學(xué)意義。 結(jié)論健康教育聯(lián)合口服補液鹽治療兒童OH近期療效明顯,可改善直立不耐受癥狀。
[Abstract]:Objective to study the efficacy of health education combined with oral rehydration salt in the treatment of orthostatic hypotension (OH) in children and its effect on the results of vertical tilt test (HUTT). Methods 51 children (30 males and 21 females, mean 9.82 鹵2.96 years) with OH were diagnosed by HUTT from 2009 to October to January 2012 in Xiangya second Hospital of Central South University. Health education and oral rehydration salt (ORS) were given to 11 patients with HUTT. after 30 days of treatment. SPSS16.0 software was used for statistical analysis and t test was used. Results after 30 days, 11 children with OH returned to hospital. The other children could not adhere to the treatment plan by telephone or were not able to return on time and the statistics were excluded. HUTT examination of 11 cases showed that 1SBP0 (supine position systolic blood pressure) comparison: there was no significant difference between before and after treatment (P < 0.05). 106.27 鹵10.82mmHg vs103.27 鹵8.91 mmHg, Comparison of 2SBP3min (systolic blood pressure in standing position 3min): after treatment, it was increased (104.91 鹵9.92mmHg vs90.55 鹵18.06 mm), (P0.05). Comparison of 3DBP0 (diastolic blood pressure in supine position): there was no significant difference before and after treatment (70.45 鹵11.79mm Hgt), and there was no significant difference between the two groups before and after treatment (70.45 鹵11.79mm). (P 0.05). Comparison of 4DBP3min (diastolic blood pressure during standing 3min): after treatment, it increased (70.00 鹵6.15mmHg vs55.18 鹵12.77mm). Comparison of 5 SBP=SBPO-SBP3min (HUTT3min systolic blood pressure decrease): the decrease of SBP after treatment was significantly lower than that before treatment (-1.64 鹵6.23mmHg vs15.73 鹵15.10 mm SBP 3.525, P < 0.05). Comparison of 6 DBP=DBPO-DBP3min (HUTT3min diastolic blood pressure decrease): the decrease of DBP after treatment was significantly lower than that before treatment (-2.73 鹵11.10mmHg vs15.27 鹵11.24 mm DBP 3.778, P < 0.05). (P0.05). 7HRO (heart rate before HUTT began to lie down): there was no significant difference in HR before and after treatment (84.73 鹵14.46 / min vs85.73 鹵9.65 / min,t=-0.191,P0.05); Comparison of HR3min (heart rate at 3min after HUTT): there was no significant difference in HR3min before and after treatment (94.27 鹵15.96 / min vs105.18 鹵6.69 / min,t=-2.090,P0.05). 8 SBP0,SBP3min,DBP0,DBP3min,HR0, before and after treatment HR3min, SBP and DBP comparison: there was no statistical difference between them (P0.05). 9 comparison of SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min,ASBP and ADBP after different sex treatment: the decrease of SBP in male was smaller than that in female (-6.00 鹵2.24mmHg vs2.00 鹵6.23mm). There was no significant difference in SBP0,SBP3min,DBP0,DBP3min,HR0,HR3min, DBP between male and female. Conclusion Health education combined with oral rehydration salt can improve the symptoms of orthostatic intolerance in children with OH.
【學(xué)位授予單位】:中南大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2012
【分類號】:R725.4

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1 Praveen Kumar;胡春艷;王成;劉曉燕;吳禮嘉;李茗香;曹閩京;林萍;崔曉麗;;兒童不明原因胸悶和(或)胸痛與直立傾斜試驗的關(guān)系[J];實用兒科臨床雜志;2009年01期



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