新生兒缺氧缺血性腦病神經保護研究現狀
發(fā)布時間:2018-09-19 13:39
【摘要】:正在過去的幾十年中,新生兒缺氧缺血性腦病(HIE)損傷后神經保護和神經康復的臨床和基礎研究取得了巨大進步。然而,就新生兒特異性的神經保護措施方面,除亞低溫治療已廣泛應用于臨床外[1-2],其他治療措施距離臨床推廣應用尚有一段距離,不同學者持有許多不同的觀點,因此,神經保護策略仍然需要更深入的研究[3]。由于HIE發(fā)生發(fā)展是一個漸進的過程,根據其所處階段不同,其治療靶點也不盡相同,如何確定最佳的治
[Abstract]:In the past few decades, great progress has been made in the clinical and basic research of neuroprotection and neurorehabilitation after (HIE) injury in neonates with hypoxic-ischemic encephalopathy (HIE). However, in terms of specific neuroprotective measures for newborns, in addition to mild hypothermia treatment has been widely used in clinical [1-2], other treatment measures are still some distance from clinical application, different scholars hold many different views, therefore, Neuroprotective strategies still need further study [3]. Because the occurrence and development of HIE is a gradual process, according to its different stages, its therapeutic targets are not the same, so how to determine the best treatment?
【作者單位】: 山東大學附屬濟南市中心醫(yī)院中心實驗室;山東省移植與組織工程研究中心;
【基金】:國家青年科學基金項目(81200950) 山東省科技發(fā)展計劃(2014GSF118173) 中國博士后科學基金面上項目(2016M590637) 山東省醫(yī)藥衛(wèi)生科技發(fā)展計劃(2016WS0139)
【分類號】:R742
本文編號:2250286
[Abstract]:In the past few decades, great progress has been made in the clinical and basic research of neuroprotection and neurorehabilitation after (HIE) injury in neonates with hypoxic-ischemic encephalopathy (HIE). However, in terms of specific neuroprotective measures for newborns, in addition to mild hypothermia treatment has been widely used in clinical [1-2], other treatment measures are still some distance from clinical application, different scholars hold many different views, therefore, Neuroprotective strategies still need further study [3]. Because the occurrence and development of HIE is a gradual process, according to its different stages, its therapeutic targets are not the same, so how to determine the best treatment?
【作者單位】: 山東大學附屬濟南市中心醫(yī)院中心實驗室;山東省移植與組織工程研究中心;
【基金】:國家青年科學基金項目(81200950) 山東省科技發(fā)展計劃(2014GSF118173) 中國博士后科學基金面上項目(2016M590637) 山東省醫(yī)藥衛(wèi)生科技發(fā)展計劃(2016WS0139)
【分類號】:R742
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