【摘要】：【目的】觀察右美托咪定與的舒芬太尼鼻內(nèi)給藥用于兒童門診手術(shù)的鎮(zhèn)靜效果�！痉椒ā繑M行口腔科門診手術(shù)的患兒60例,年齡3~7歲,體質(zhì)量10~32 kg,性別不限,ASA分級Ⅰ-Ⅱ級。采用隨機(jī)數(shù)字表法,將患兒分為3組(n=20),右美托咪定聯(lián)合舒芬太尼組(DS組),右美托咪定組(D組)和舒芬太尼組(S組),于術(shù)前準(zhǔn)備室內(nèi)分別經(jīng)鼻予以右美托咪定2μg/kg和舒芬太尼1μg/kg;右美托咪定2μg/kg;舒芬太尼1μg/kg。記錄入室時、術(shù)中、出室時和PACU中的俄亥俄州大學(xué)行為級別評分(OSUBRS)、密歇根州大學(xué)鎮(zhèn)靜評分(UMSS)。記錄患兒用藥前后的收縮壓、心率和用藥后不良反應(yīng)。【結(jié)果】入室時和術(shù)中的OSUBRS評分DS組低于D組和S組(P0.01);UMSS均高于D組和S組(P0.05)。DS組的鎮(zhèn)靜成功率高于D組和S組(P0.01)。DS組與D組用藥后收縮壓和心率下降的百分?jǐn)?shù)無統(tǒng)計學(xué)差異(P0.05)。沒有患兒發(fā)生呼吸抑制、低血壓和心動過緩�！窘Y(jié)論】右美托咪定與舒芬太尼鼻內(nèi)給藥可為兒童口腔科門診手術(shù)提供滿意的鎮(zhèn)靜,并不伴有呼吸抑制、心動過緩和低血壓的不良反應(yīng)。
[Abstract]:[objective] to observe the sedation effect of dexmetoimidine and sufentanil for pediatric outpatient surgery. [methods] A total of 60 children, aged 37 years, with a body mass of 1032 kg, were enrolled in pediatric outpatient surgery. Using random digital tables, The children were divided into 3 groups: dexmetomidine combined with sufentanil (DS group), dexmetomidine group (D group) and sufentanil group (S group). The patients were given 2 渭 g/kg and 1 渭 g / kg sufentanil, 2 渭 g / kg, 2 渭 g / kg, 1 渭 g / kg, respectively. Record entry time, intraoperative, intraventricular and PACU behavioral grade scores at the University of Ohio, (OSUBRS), University of Michigan sedation score (UMSS). Systolic blood pressure was recorded before and after medication. Heart rate and adverse reaction after medication. [results] the OSUBRS scores of group DS at room entry and during operation were lower than those of group D and group S (P0.01). The sedation success rate of group DS was higher than that of group D and group S (P0.05). The success rate of sedation in group DS was higher than that in group D and group S (P0.01). There was no statistical difference in the percentage of heart rate decrease (P0.05). No children developed respiratory depression, hypotension and bradycardia. [conclusion] Intranasal administration of dexmetomidine and sufentanil can provide satisfactory sedation for pediatric stomatological outpatient surgery without respiratory inhibition. Adverse effects of palliative hypotension.
【作者單位】： 武警后勤學(xué)院附屬醫(yī)院麻醉科;
【基金】：武警后勤學(xué)院附屬醫(yī)院面上項目(FYM201550)
【分類號】：R726.1

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