發(fā)布時(shí)間：2018-08-25 14:17

【摘要】：目的探討兒童嗜酸細(xì)胞性膀胱炎的臨床、病理特點(diǎn)及診斷和治療。方法回顧分析2012年至2016年收治的7例嗜酸細(xì)胞性膀胱炎患兒的臨床資料,并復(fù)習(xí)相關(guān)文獻(xiàn)。結(jié)果 7例患兒的中位年齡為9歲,臨床表現(xiàn)為尿急、尿頻、尿痛、血尿、下腹痛、夜間遺尿等。超聲和CT檢查示膀胱壁增厚和占位性病變。7例患兒通過(guò)膀胱活組織檢查均符合嗜酸細(xì)胞性膀胱炎;6例患兒經(jīng)藥物治療后在2個(gè)月內(nèi)痊愈,另1例反復(fù)藥物治療1年痊愈。隨訪3個(gè)月~4年,排尿異常癥狀消失,影像學(xué)檢查膀胱異常變化消失。結(jié)論兒童嗜酸細(xì)胞性膀胱炎為良性病變,與膀胱腫瘤的臨床表現(xiàn)極為相似,確診靠組織活檢外,也可根據(jù)臨床表現(xiàn)、實(shí)驗(yàn)室檢查及治療效果;治療以激素、抗組胺、抗炎藥物為主。
[Abstract]:Objective To investigate the clinical, pathological features, diagnosis and treatment of eosinophilic cystitis in children.Methods The clinical data of 7 children with eosinophilic cystitis admitted from 2012 to 2016 were analyzed retrospectively.Results The median age of the 7 children was 9 years old.The clinical manifestations were acute urination, frequent urination, urinary pain, hematuria, lower abdominal pain and nocturnal pain. Ultrasonography and CT showed thickening of bladder wall and space occupying lesions.7 cases of children with bladder biopsy were accorded with eosinophilic cystitis.6 cases were cured within 2 months after drug treatment,another case was cured after repeated drug treatment for 1 year.Follow-up for 3 months to 4 years,the abnormal urination symptoms disappeared and the abnormal changes of bladder were eliminated by imaging examination. Conclusion Eosinophilic cystitis in children is a benign lesion, which is very similar to the clinical manifestations of bladder tumor. The diagnosis depends on biopsy, clinical manifestations, laboratory examination and therapeutic effect. The treatment is mainly hormones, antihistamines and anti-inflammatory drugs.
【作者單位】： 鄭州大學(xué)第一附屬醫(yī)院;
【分類(lèi)號(hào)】：R726.9

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