【摘要】：目的了解不同碘營養(yǎng)水平兒童甲狀腺結(jié)節(jié)患病情況,探討碘過量對兒童甲狀腺結(jié)節(jié)類型的影響。方法選擇供碘鹽地區(qū)的3個(gè)縣調(diào)查,每個(gè)縣隨機(jī)抽取8-10歲學(xué)生(男、女各半)200人;在水源性高碘地區(qū)抽取水碘含量100-1 100μg/L的13村為調(diào)查點(diǎn),每個(gè)調(diào)查點(diǎn)隨機(jī)抽取學(xué)校8-10歲學(xué)生(男、女各半)100名。對抽取的學(xué)生隨機(jī)采集1次性尿樣檢測尿碘,用B超法檢測甲狀腺結(jié)節(jié)情況,對學(xué)校所在的村隨機(jī)采集2份末梢水樣檢測水碘。結(jié)果檢查2 092名8-10歲兒童的甲狀腺,檢出甲狀腺結(jié)節(jié)患者138例,甲狀腺結(jié)節(jié)總檢出率為6.6%。其中,實(shí)質(zhì)性結(jié)節(jié)占82.6%(114/138),囊實(shí)性占16.7%(23/138),囊性占0.7%(1/138)。尿碘中位數(shù)100-299μg/L、300-699μg/L、700-1 163μg/L的兒童甲狀腺結(jié)節(jié)檢出率經(jīng)統(tǒng)計(jì)有顯著差異(χ~2=22.17,P0.01);甲狀腺實(shí)質(zhì)性結(jié)節(jié)所占比例無差異(χ~2=2.82,P0.05)。結(jié)論碘營養(yǎng)過量可能會(huì)造成兒童甲狀腺結(jié)節(jié)患病增加,但對甲狀腺結(jié)節(jié)的囊、實(shí)性患病可能無影響。
[Abstract]:Objective to investigate the prevalence of thyroid nodules in children with different iodine nutrition levels and to explore the effect of iodine excess on thyroid nodules in children. Methods A total of 200 students (male and half female) aged 8 to 10 years old were randomly selected from 3 counties in iodized salt area, and 13 villages with 100 ~ 1 100 渭 g / L iodine content in water source high iodine area were selected as investigation points. A random sample of 100 school students aged 8-10 years (male and half female) was randomly selected from each survey site. Urine iodine was detected by random sampling of urine samples from students, thyroid nodule was detected by B-ultrasound, and iodine was detected by 2 samples of peripheral water in the village where the school was located. Results the thyroid gland of 2 092 children aged 8 to 10 years was examined, 138 cases of thyroid nodules were detected, the total detection rate of thyroid nodules was 6. 6%. Of these, 82.6% (114 / 138) were parenchymal nodules, 16.7% (23 / 138) were cystic, and 0.7% (1 / 138) were cystic. There was significant difference in the detection rate of thyroid nodules between 300-699 渭 g / L and 700-1 163 渭 g / L in children with urinary iodine median of 100-299 渭 g / L (蠂 ~ 2 = 22.17 / P 0.01), but there was no significant difference in the proportion of thyroid parenchymal nodules (蠂 ~ (2) 2.82 ~ (2) P ~ (0.05). Conclusion excessive iodine nutrition may increase the incidence of thyroid nodules in children, but there may be no effect on the solid disease of thyroid nodules.
【作者單位】： 滄州市疾病預(yù)防控制中心;河北省疾病預(yù)防控制中心地方病防治所;
【分類號】：R725.8

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